SCHEMBL30249043

SCHEMBL30249043

CN(C)CCc1c[nH]c2cc3c(cc12)OCO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 11/20 1.00
HTR1A P08908 9/20 1.00
HTR2C P28335 8/20 1.00
HTR2A P28223 8/20 1.00
HTR1B P28222 8/20 1.00
HTR2B P41595 6/20 1.00
HTR6 P50406 5/20 1.00
HTR3E A5X5Y0 4/20 1.00
HTR3B O95264 4/20 1.00
HTR1E P28566 4/20 1.00
HTR1F P30939 4/20 1.00
HTR7 P34969 4/20 1.00
HTR3A P46098 4/20 1.00
HTR5A P47898 4/20 1.00
HTR4 Q13639 4/20 1.00
HTR3D Q70Z44 4/20 1.00
HTR3C Q8WXA8 4/20 1.00
MPO P05164 1/20 0.55
SLC6A4 P31645 1/20 0.55
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20970981 1.00 HTR1D (1.00) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL23069130 0.86 HTR1D (0.75) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL2409566 0.85 HTR1D (0.73) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL20970979 0.84 HTR1D (0.72) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL29633043 0.84 HTR1D (0.72) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL20970917 0.82 HTR1D (0.69) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL30249112 0.82 HTR1D (0.69) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL25747780 0.82 HTR1D (0.86) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL1973250 0.80 HTR2A (0.66) HTR1DHTR1AHTR2CHTR2AHTR1B
SCHEMBL32669398 0.80 HTR1A (0.66) HTR1DHTR1AHTR2CHTR2AHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 WO claimed
EP-4704806-A1 INJECTABLE PHARMACEUTICAL FORMULATIONS Cybin IRL Limited (IE) 2026-03-11 EP disclosed
US-20260034119-A1 5-METHOXY-N,N-DIMETHYLTRYPTAMINE ANALOGS, THEIR SYNTHESIS, AND METHODS FOR TREATMENT OF NEUROLOGICAL, PSYCHIATRIC, AND SUBSTANCE USE DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2026-02-05 US disclosed
WO-2024251807-A1 COMPANION ANIMAL TREATMENTS CYBIN IRL LIMITED (IE) 2024-12-12 WO disclosed
WO-2024231331-A1 INJECTABLE PHARMACEUTICAL FORMULATIONS CYBIN IRL LIMITED (IE) 2024-11-14 WO disclosed
EP-4452986-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-10-30 EP disclosed
EP-4392027-A2 FLUORINATED EMPATHOGENS Alexander Shulgin Research Institute, Inc. (US) 2024-07-03 EP disclosed
WO-2023225043-A1 TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-11-23 WO disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 WO disclosed
WO-2023028092-A2 FLUORINATED EMPATHOGENS ALEXANDER SHULGIN RESEARCH INSTITUTE (US) 2023-03-02 WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034119-A1 5-METHOXY-N,N-DIMETHYLTRYPTAMINE ANALOGS, THEIR SYNTHESIS, AND METHODS FOR TREATMENT OF NEUROLOGICAL, PSYCHIATRIC, AND SUBSTANCE USE DISORDERS HTR4, OPRM1, HTR7 HTR1D 11/4885HTR1A 4/4885HTR2C 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.