Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066294 | 0.91 | GAA (0.50) | TSHRRAB9ANPC1LMNANPSR1 | |
| SCHEMBL878536 | 0.83 | ALDH1A1 (0.61) | RAB9ATDP1KMT2AGAAHSD17B10 | |
| SCHEMBL5696260 | 0.82 | SERPINE1 (0.43) | TSHRLMNATDP1ESR1KMT2A | |
| SCHEMBL30524282 | 0.82 | SERPINE1 (0.43) | TSHRLMNATDP1ESR1KMT2A | |
| SCHEMBL9257525 | 0.78 | LDHA (0.49) | RAB9ANPC1LMNATDP1KMT2A | |
| SCHEMBL7197218 | 0.78 | NCEH1 (0.46) | RAB9ANPC1LMNATDP1GAA | |
| SCHEMBL2638148 | 0.78 | ESR1 (0.48) | TSHRRAB9ANPC1LMNAPKM | |
| SCHEMBL9035250 | 0.77 | LMNA (0.44) | TSHRLMNAHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL11863351 | 0.77 | NCEH1 (0.65) | TSHRRAB9ANPC1LMNANPSR1 | |
| SCHEMBL4444465 | 0.76 | HTT (0.61) | TSHRRAB9ANPC1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246551-A2 | Bis-benzoxazolylnaphthalenes containing sulfonate or sulfonamide groups, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-25 | — | — | EP | claimed |
| EP-0002030-B1 | FLUORINATED BENZAZOLE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-30 | — | — | EP | disclosed |
| EP-0002030-A1 | Fluorinated benzazole derivatives, method for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-30 | — | — | EP | disclosed |