Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8301078 | 0.98 | LMNA (0.43) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL2309532 | 0.84 | CYP1A2 (0.45) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL30511914 | 0.83 | PTPN1 (0.51) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL29380815 | 0.83 | NCF1 (0.47) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL6631053 | 0.83 | NCF1 (0.47) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL13434056 | 0.83 | PTPN1 (0.51) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL10439987 | 0.80 | HSD17B10 (0.46) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL7362604 | 0.80 | CYP1A2 (0.42) | LMNASMN1; SMN2NCF1PTPN1PTPN11 | |
| SCHEMBL17199398 | 0.80 | MAPT (0.54) | LMNASMN1; SMN2FABP5CYP1A2ALDH1A1 | |
| SCHEMBL11717170 | 0.80 | HTR1A (0.44) | LMNASMN1; SMN2NCF1PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |