SCHEMBL578709

SCHEMBL578709

[c]1cc2c3ccccc3[c]cc2c2ccccc12

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 2/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234963 0.84 HPRT1 (0.58) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL235409 0.84 HPRT1 (0.58) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL2409141 0.84 HPRT1 (0.31)
SCHEMBL25131 0.81 ALDH1A1 (0.46) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL535426 0.79 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP1A2
SCHEMBL2408455 0.79 CYP1A2 (0.31) CYP1A2
SCHEMBL3738239 0.79 HPGD (0.38) ALDH1A1HSD17B10
SCHEMBL20560732 0.79 HPRT1 (0.31)
SCHEMBL9551471 0.79 CYP1A2 (0.48) CYP2A6ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL10796479 0.78 ALDH1A1 (0.37) CYP2A6ALDH1A1TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8629613-B2 Aromatic amine derivative and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-14 US claimed
US-11895917-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2024-02-06 US disclosed
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-12-22 US disclosed
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 US disclosed
EP-2338186-B1 ORGANIC LIGHT EMITTING DEVICE AND MATERIALS FOR USE IN SAME UNIVERSAL DISPLAY CORP (US) 2020-02-12 EP disclosed
EP-2713415-B1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2018-12-19 EP disclosed
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-17 US disclosed
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-10 US disclosed
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-12-11 US disclosed
EP-1950193-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-07-30 EP disclosed
US-20080108811-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-05-08 US disclosed
EP-1834946-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-09-19 EP disclosed
EP-1834945-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-09-19 EP disclosed
US-20070111028-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-05-17 US disclosed
EP-1768199-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-03-28 EP disclosed
US-20060159957-A1 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2006-07-20 US disclosed
US-20060134458-A1 Aromatic amine derivative and organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2006-06-22 US disclosed
EP-1584614-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX CYP2A6 3944/4885ALDH1A1 1810/4885TSHR 4787/4885
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME PPOX, EPCAM, STOM CYP2A6 3848/4885ALDH1A1 1724/4885TSHR 4783/4885
US-20060159957-A1 Aromatic amine derivative and organic electroluminescence device employing the same OPA1, MAOA, AOC2 CYP2A6 2175/4885ALDH1A1 437/4885TSHR 4013/4885
US-20070111028-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EML4, TYR, OCIAD2 CYP2A6 3333/4885ALDH1A1 884/4885TSHR 4061/4885
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same PPOX, EPCAM, STOM CYP2A6 3848/4885ALDH1A1 1724/4885TSHR 4783/4885
US-20080108811-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same ALKBH2, ALKBH3, SETD1A CYP2A6 2500/4885ALDH1A1 779/4885TSHR 4526/4885
US-11895917-B2 Material for organic electroluminescence device and organic electroluminescence device using the same PPOX, EPCAM, STOM CYP2A6 3848/4885ALDH1A1 1724/4885TSHR 4783/4885
US-20060134458-A1 Aromatic amine derivative and organic electroluminescence element TYR, SLC18A1, MAOA CYP2A6 3087/4885ALDH1A1 689/4885TSHR 3594/4885
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same DDC, AOC2, ALKBH2 CYP2A6 3920/4885ALDH1A1 238/4885TSHR 4448/4885
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX CYP2A6 3944/4885ALDH1A1 1810/4885TSHR 4787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.