SCHEMBL107759

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29580736	0.83	CTSA (0.48)	CTSACSF1RFLT3FDPSGRM5
	SCHEMBL171083	0.83	CTSA (0.48)	CTSACSF1RFLT3FDPSGRM5
	SCHEMBL10274536	0.82	KMT2A (0.50)	CTSACSF1RFLT3MEN1KMT2A
	SCHEMBL168844	0.82	MAOB (0.51)	CTSAFLT3MEN1KMT2AKDM4E
	SCHEMBL7083262	0.82	CTSA (0.45)	CTSAMEN1KMT2AKDM4ENPC1
	SCHEMBL13852609	0.81	KMT2A (0.52)	CTSAMEN1KMT2AGRM5SMN1; SMN2
	SCHEMBL171037	0.80	EGLN1 (0.55)	CTSAMEN1KMT2AMMP13
	SCHEMBL7171815	0.79	KDM4E (0.57)	P2RX7KDM4E
	SCHEMBL15908508	0.79	KMT2A (0.45)	CTSAMEN1KMT2AKDM4ENOS3
	SCHEMBL31345733	0.79	P2RX7 (0.50)	P2RX7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.