Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MPO | P05164 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 2/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345028 | 0.87 | KDM4E (0.52) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL27212647 | 0.81 | P2RX7 (0.50) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL2635589 | 0.81 | KDM4E (0.57) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL17850259 | 0.81 | P2RX7 (0.50) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL1417739 | 0.81 | GABRP (0.63) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL31345733 | 0.81 | P2RX7 (0.50) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL4002804 | 0.81 | KDM4E (0.45) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL4008467 | 0.81 | KDM4E (0.45) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL1505656 | 0.79 | ALDH1A1 (0.61) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL2997667 | 0.79 | KDM4E (0.55) | KDM4EMPOCYP3A4CYP1A2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021075528-A1 | METHOD FOR EVALUATING DRUG TOXICITY | 公立大学法人横浜市立大学 | 2021-04-22 | — | — | WO | disclosed |
| WO-2003053347-A2 | GALLIUMCOMPLEXES OF 3-HYDROXY-4-PYRONES TO TREAT MYCOBACTERIAL INFECTIONS | BERNSTEIN LAWRENCE R (US) | 2003-07-03 | — | — | WO | disclosed |
| US-20020068761-A1 | Gallium complexes of 3-hydroxy-4-pyrones to treat mycobacterial infections | BERNSTEIN LAWRENCE R (US) | 2002-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068761-A1 | Gallium complexes of 3-hydroxy-4-pyrones to treat mycobacterial infections | PGLS, MDH1, GCDH | KDM4E 757/4885MPO 1404/4885CYP3A4 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.