Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tymazoline SCHEMBL29387735 | 0.80 | NISCH (0.70) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| Tymazoline SCHEMBL250491 | 0.80 | NISCH (0.70) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| Tymazoline SCHEMBL4415590 | 0.79 | NISCH (0.68) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| Tymazoline SCHEMBL28142132 | 0.75 | NISCH (0.81) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| Fenoxazoline SCHEMBL1650113 | 0.74 | NISCH (0.97) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| SCHEMBL11265817 | 0.74 | NISCH (0.58) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| SCHEMBL11265808 | 0.74 | NISCH (0.60) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| SCHEMBL12129212 | 0.73 | TSHR (0.52) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL3962998 | 0.71 | NISCH (0.74) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| SCHEMBL3163294 | 0.70 | WDR5 (0.57) | NISCHADRA1AADRA1DADRA1BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086428-B1 | ANTIDIARRHOEA VETERINARY COMPOSITION, ITS PRODUCTION AND ORAL DOSER CONTAINING IT | BEECHAM GROUP PLC (GB) | 1987-07-29 | — | — | EP | disclosed |