Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tymazoline SCHEMBL250491 | 0.94 | NISCH (0.70) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| Tymazoline SCHEMBL29387735 | 0.94 | NISCH (0.70) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| Tymazoline SCHEMBL4415590 | 0.93 | NISCH (0.68) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| Fenoxazoline SCHEMBL193061 | 0.90 | NISCH (1.00) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| Fenoxazoline SCHEMBL1650113 | 0.89 | NISCH (0.97) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| Fenoxazoline SCHEMBL317133 | 0.89 | NISCH (0.97) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL7982763 | 0.82 | NISCH (0.56) | NISCHADRA1AADRA1BADRA1DADRA2A | |
| Fenoxazoline SCHEMBL28086604 | 0.78 | NISCH (0.74) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL11265817 | 0.76 | NISCH (0.58) | NISCHADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL10777341 | 0.75 | NISCH (0.60) | NISCHADRA1AADRA1BADRA1DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |