Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18321311 | 1.00 | KMT2A (0.54) | KMT2ATSHRNPC1RAB9AHTR2A | |
| SCHEMBL10778105 | 0.87 | TSHR (0.53) | KMT2ATSHRNPC1RAB9ALMNA | |
| SCHEMBL23368144 | 0.84 | TSHR (0.54) | KMT2ATSHRNPC1RAB9ALMNA | |
| SCHEMBL18331090 | 0.84 | TSHR (0.54) | KMT2ATSHRNPC1RAB9ALMNA | |
| SCHEMBL11335162 | 0.82 | KMT2A (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10781651 | 0.80 | LMNA (0.63) | KMT2ATSHRNPC1RAB9ALMNA | |
| SCHEMBL571602 | 0.80 | KDM4E (0.63) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL9129132 | 0.80 | TSHR (0.58) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL503699 | 0.80 | KMT2A (0.66) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL8935734 | 0.80 | KMT2A (0.66) | KMT2ATSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820425-B | Compounds for the treatment of neuromuscular disorders | NMD制药股份公司 | 2021-08-31 | — | — | CN | disclosed |
| EP-3307262-B1 | COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS | NMD PHARMA AS (DK) | 2021-05-19 | — | — | EP | disclosed |
| US-9447134-B2 | Compounds and methods for treating mammalian gastrointestinal microbial infections | BRANDEIS UNIVERSITY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150210727-A1 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-07-30 | — | — | US | disclosed |
| WO-2014028931-A2 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2014-02-20 | — | — | WO | disclosed |
| EP-0109311-B1 | N,N-DIALKYL-2-(4'-SUBSTITUTED-1'-NAPHTHOXY)PROPIONAMIDES | STAUFFER CHEMICAL COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |
| US-4548641-A | PREEMERGENCE HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210727-A1 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | IMPDH1, IMPDH2, IMPA1 | KMT2A 3718/4885TSHR 4744/4885NPC1 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.