Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESRRA | P11474 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18331090 | 1.00 | TSHR (0.54) | TSHRNPC1RAB9ALMNAESRRA | |
| SCHEMBL18321311 | 0.84 | KMT2A (0.54) | TSHRNPC1RAB9ALMNAESRRA | |
| SCHEMBL10778046 | 0.84 | KMT2A (0.54) | TSHRNPC1RAB9ALMNAESRRA | |
| SCHEMBL10778105 | 0.84 | TSHR (0.53) | TSHRNPC1RAB9ALMNAESRRA | |
| SCHEMBL28729952 | 0.81 | KMT2A (0.56) | LMNAKMT2AMEN1MAPTL3MBTL1 | |
| Lonaprofen SCHEMBL2109183 | 0.79 | NCEH1 (0.56) | NPC1RAB9ALMNAKMT2AMEN1 | |
| Lonaprofen SCHEMBL29670159 | 0.79 | NCEH1 (0.56) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL9563096 | 0.79 | PKM (0.49) | TSHRLMNAESRRAKMT2AMEN1 | |
| SCHEMBL10781651 | 0.77 | LMNA (0.63) | TSHRNPC1RAB9ALMNAESRRA | |
| SCHEMBL9711019 | 0.77 | F9 (0.51) | KMT2AMEN1MAPTF9PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307262-B1 | COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS | NMD PHARMA AS (DK) | 2021-05-19 | — | — | EP | disclosed |