SCHEMBL10778684

SCHEMBL10778684

CCCCCCNC(=O)c1ccc(N)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.73
NAAA Q02083 2/20 0.71
CA2 P00918 1/20 0.68
MLYCD O95822 1/20 0.66
THRA P10827 1/20 0.61
THRB P10828 1/20 0.61
ALDH1A1 P00352 4/20 0.60
LMNA P02545 2/20 0.60
MAPK1 P28482 2/20 0.60
SLC22A2 O15244 1/20 0.60
SLC22A1 O15245 1/20 0.60
TSHR P16473 1/20 0.60
ACHE P22303 1/20 0.60
CYP2C19 P33261 1/20 0.60
MAPT P10636 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
BLM P54132 1/20 0.59
PMP22 Q01453 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9645769 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL11611741 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL11618437 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL11612802 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL1852359 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL9164780 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL11139136 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL11617865 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL11614197 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA
SCHEMBL11614082 1.00 L3MBTL1 (0.73) L3MBTL1NAAACA2MLYCDTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0078845-B1 ANTI-CONVULSANT CLARK, Charles Randall (US) 1987-02-04 EP claimed
EP-0078845-A4 ANTI-CONVULSANT. CLARK CHARLES RANDALL 1983-09-02 EP claimed
EP-0078845-A1 ANTI-CONVULSANT. CLARK CHARLES RANDALL 1983-05-18 EP claimed
US-4379165-A Anti-convulsant RESEARCH CORPORATION (US) 1983-04-05 US claimed
WO-1982004046-A1 ANTI-CONVULSANT CLARK CHARLES RANDALL 1982-11-25 WO claimed
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2025-01-30 US disclosed
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity PHARMA CINQ, LLC (US) 2024-11-12 US disclosed
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2021-06-03 US disclosed
EP-3350350-B1 COMPOUNDS AND SYSTEMS FOR IMPROVING SIGNAL DETECTION PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2021-04-14 EP disclosed
US-10934284-B2 Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity WELLSTAT THERAPEUTICS CORPORATION (US) 2021-03-02 US disclosed
CN-108250142-B Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity 维尔斯达医疗公司 2021-01-26 CN disclosed
EP-3632426-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY Wellstat Therapeutics Corporation (US) 2020-04-08 EP disclosed
WO-2014120995-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY WELLSTAT THERAPEUTICS CORPORATION (US) 2014-08-07 WO disclosed
EP-0078845-B1 ANTI-CONVULSANT CLARK, Charles Randall (US) 1987-02-04 EP disclosed
US-4467085-A CHROMOGEN BONDED TO POLYMERS Scharf, Gerhard (DE) 1984-08-21 US disclosed
EP-0078845-A4 ANTI-CONVULSANT. CLARK CHARLES RANDALL 1983-09-02 EP disclosed
EP-0078845-A1 ANTI-CONVULSANT. CLARK CHARLES RANDALL 1983-05-18 EP disclosed
US-4379165-A Anti-convulsant RESEARCH CORPORATION (US) 1983-04-05 US disclosed
WO-1982004046-A1 ANTI-CONVULSANT CLARK CHARLES RANDALL 1982-11-25 WO disclosed
US-4329283-A DISPERSE DYES BAYER AKTIENGESELLSCHAFT (DE) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY NOD1, NLRP3, AADAC L3MBTL1 1523/4885NAAA 343/4885CA2 3391/4885
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY AADAC, CASP1, AAAS L3MBTL1 1868/4885NAAA 106/4885CA2 3725/4885
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity NOD1, NLRP3, AADAC L3MBTL1 1523/4885NAAA 343/4885CA2 3391/4885
US-10934284-B2 Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity AAAS, AADAC, NFKBIA L3MBTL1 2833/4885NAAA 343/4885CA2 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.