Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496338 | 0.89 | SMN1; SMN2 (0.51) | ADORA2AADORA1LMNAGAAKDM4E | |
| SCHEMBL16752107 | 0.89 | ADORA2A (0.48) | ADORA2AADORA1LMNAGAAPGR | |
| SCHEMBL1931354 | 0.81 | KDM4E (0.51) | ADORA2AADORA1LMNAGAAKDM4E | |
| SCHEMBL2025571 | 0.81 | PGR (0.43) | ADORA2AADORA1LMNAGAAPGR | |
| SCHEMBL27684874 | 0.79 | LMNA (0.49) | ADORA2AADORA1LMNAGAAKDM4E | |
| SCHEMBL10776096 | 0.79 | PGR (0.48) | ADORA2AADORA1LMNAPGRADRA2A | |
| SCHEMBL3205527 | 0.79 | TDP1 (0.48) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL20867847 | 0.78 | PGR (0.47) | ADORA2AADORA1LMNAPGRADRA2A | |
| SCHEMBL6298510 | 0.78 | LMNA (0.47) | ADORA2AADORA1LMNAGAAKDM4E | |
| SCHEMBL2311192 | 0.78 | EPHX1 (0.66) | ADORA2AADORA1LMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249365-A2 | Photocatalysts for vinyl compounds activated by an electron donating hetero atom | LOCTITE (IRELAND) Ltd. (IE) | 1987-12-16 | — | — | EP | disclosed |