Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22390702 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| SCHEMBL22390704 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| SCHEMBL9107945 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| SCHEMBL10620092 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| SCHEMBL3500948 | 0.75 | MAPT (0.55) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| SCHEMBL973244 | 0.75 | MAPT (0.55) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| SCHEMBL973245 | 0.75 | MAPT (0.55) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| Water SCHEMBL5373028 | 0.74 | MAPT (0.53) | ALDH1A1CHRNA7CHRNA10CHRNA9TDP1 | |
| SCHEMBL13803508 | 0.72 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRMAPK1HSD17B10 | |
| SCHEMBL10598054 | 0.72 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134446-B1 | NEGATIVE PHOTORESIST FORMULATIONS WITH RADIATION-ABSORBING ADDITIVES | MERCK PATENT GmbH (DE) | 1987-05-20 | — | — | EP | disclosed |