SCHEMBL1077970

SCHEMBL1077970

O=[N+]([O-])c1cccc([N+](=O)[O-])c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 3/20 1.00
ERN1 O75460 1/20 0.67
TDP1 Q9NUW8 3/20 0.61
CRHBP P24387 1/20 0.57
CRHR2 Q13324 1/20 0.57
TSHR P16473 2/20 0.52
ALDH1A1 P00352 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
CXCR1 P25024 1/20 0.51
CXCR2 P25025 1/20 0.51
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
GLA P06280 1/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11228321 0.97 GPR35 (0.95) GPR35ERN1TDP1CRHBPCRHR2
SCHEMBL30135314 0.97 GPR35 (0.95) GPR35ERN1TDP1CRHBPCRHR2
SCHEMBL11228314 0.97 GPR35 (0.95) GPR35ERN1TDP1CRHBPCRHR2
SCHEMBL70167 0.88 GPR35 (0.78) GPR35ERN1TDP1CRHBPCRHR2
SCHEMBL11309776 0.88 GPR35 (0.78) GPR35ERN1TDP1CRHBPCRHR2
SCHEMBL4071134 0.86 GPR35 (0.75) GPR35ERN1TDP1CRHBPCRHR2
Toluene SCHEMBL28998637 0.85 GPR35 (0.73) GPR35ERN1TDP1CRHBPCRHR2
SCHEMBL846242 0.84 GPR35 (0.72) GPR35ERN1TDP1CRHBPCRHR2
SCHEMBL103754 0.84 GPR35 (0.72) GPR35ERN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL102078 0.84 GPR35 (0.72) GPR35ERN1TDP1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
US-20260108476-A1 2,4 DNP and Prodrugs Thereof for Treatment of Cancer MITOCHON PHARMACEUTICALS, INC. (US) 2026-04-23 US claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO claimed
CN-118010870-A Method for simultaneously measuring multiple nitrophenol compounds in different food matrixes 四川省食品检验研究院 2024-05-10 CN claimed
WO-2023205625-A2 2,4 DNP AND PRODRUGS THEREOF FOR TREATMENT OF PULMONARY AND AUTOIMMUNE DISEASES MITOCHON PHARMACEUTICALS, INC. (US) 2023-10-26 WO claimed
CN-114235541-B Method for rapidly determining 12 nitrophenol compounds in industrial wastewater 甘肃中商食品质量检验检测有限公司 2023-09-22 CN claimed
WO-2023092175-A1 NOVEL P2X7 RECEPTOR ANTAGONISTS THE UNIVERSITY OF SYDNEY (AU) 2023-06-01 WO claimed
US-11629373-B2 Compositions, systems, and methods for detecting the presence of polymer subunits using chemiluminescence ILLUMINA, INC. (US) 2023-04-18 US claimed
US-20230100940-A1 DNP and DNP Prodrug Treatment of Neuromuscular, Neurodegenerative, Autoimmune, Developmental, Traumatic Brain Injury, Concussion, Dry Eye Disease, Hearing Loss and/or Metabolic Diseases MITOCHON PHARMACEUTICALS, INC. (US) 2023-03-30 US claimed
EP-0352489-B1 USE OF 2,6-DINITROPHENOL DERIVATIVES IN HAIR DYEING COMPOSITIONS Wella Aktiengesellschaft (DE) 1992-06-17 EP claimed
EP-0244799-B1 AN ELECTROLYTE FOR ELECTROLYTIC CAPACITOR NIPPON CHEMI-CON CORPORATION (JP) 1991-03-06 EP claimed
US-4975093-A Hair dyeing compositions containing 2,6-dinitro-phenol-derivatives WELLA AKTIENGESELLSCHAFT (DE) 1990-12-04 US claimed
US-4830785-A ALKYL AMMONIUM OR AMINE SALTS OF PHENOL OR NITROPHENOL IN APROTIC SOLVENTS NIPPON CHEMI-CON CORPORATION (JP) 1989-05-16 US claimed
US-4724234-A ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION THERAPEUTICAL SYSTEMS CORP. (US) 1988-02-09 US claimed
US-4724230-A Method for producing oncolysis THERAPEUTICAL SYSTEMS CORP. (US) 1988-02-09 US claimed
EP-0244799-A2 An electrolyte for electrolytic capacitor NIPPON CHEMI-CON CORPORATION (JP) 1987-11-11 EP claimed
US-4460717-A COATING FOUNDRY AGGREGATE WITH PHENOLIC RESIN CONTAINING AN AROMATIC COMPOUND SUMITOMO DUREZ COMPANY, LTD. (JP) 1984-07-17 US claimed
US-4170669-A ACID- OR BASE-SOLUBILE OKADA ICHIRO (JP) 1979-10-09 US claimed
US-4115652-A Process for the preparation of amino-nitrophenols BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230100940-A1 DNP and DNP Prodrug Treatment of Neuromuscular, Neurodegenerative, Autoimmune, Developmental, Traumatic Brain Injury, Concussion, Dry Eye Disease, Hearing Loss and/or Metabolic Diseases SMN1; SMN2, MYLK2, WFS1 GPR35 2363/4885ERN1 4205/4885TDP1 42/4885
US-20260108476-A1 2,4 DNP and Prodrugs Thereof for Treatment of Cancer DNPH1, SLC5A2, DNPEP GPR35 2262/4885ERN1 4620/4885TDP1 1933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.