Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.72 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329816 | 0.98 | GPR35 (0.69) | GPR35ERN1TDP1HPGDMEN1 | |
| SCHEMBL1077970 | 0.84 | GPR35 (1.00) | GPR35ERN1TDP1MEN1KMT2A | |
| SCHEMBL30135314 | 0.82 | GPR35 (0.95) | GPR35ERN1TDP1MEN1KMT2A | |
| SCHEMBL11228314 | 0.82 | GPR35 (0.95) | GPR35ERN1TDP1MEN1KMT2A | |
| SCHEMBL11228321 | 0.82 | GPR35 (0.95) | GPR35ERN1TDP1MEN1KMT2A | |
| 2,6-Dichlorophenol SCHEMBL10638279 | 0.80 | GPR35 (0.48) | GPR35ERN1TDP1MEN1KMT2A | |
| Pentachlorophenol SCHEMBL10585537 | 0.79 | GPR35 (0.53) | GPR35ERN1TDP1HPGDMEN1 | |
| SCHEMBL58157 | 0.78 | TDP1 (0.65) | GPR35TDP1HPGDMEN1KMT2A | |
| SCHEMBL70167 | 0.78 | GPR35 (0.78) | GPR35ERN1TDP1HPGDMEN1 | |
| SCHEMBL29460277 | 0.78 | TDP1 (0.65) | GPR35TDP1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041201-A | A kind of preparation method of the chloro- 6- nitrophenol of oxyclozanide intermediate 2,4- bis- | 常州齐晖药业有限公司 | 2019-07-23 | — | — | CN | claimed |
| CN-108059602-A | A kind of preparation method of oxyclozanide intermediate 2-amino -4,6- chlorophenesic acid organic solution | 常州齐晖药业有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-105621587-B | A kind of method using potentiometric titrations degradating chloro nitro-aromatic | 浙江大学 | 2018-01-23 | — | — | CN | claimed |
| CN-105621587-A | Method for degrading chloro-nitroaromatic by using sulfate radicals | UNIV ZHEJIANG | 2016-06-01 | — | — | CN | claimed |
| CN-101914028-B | Method for preparing 2-amido-4,6-dichlorophenol | UNIV CHANGZHOU | 2013-08-14 | — | — | CN | claimed |
| CN-101914028-A | Method for preparing 2-amido-4,6-dichlorophenol | UNIV CHANGZHOU | 2010-12-15 | — | — | CN | claimed |
| CN-101184730-A | New hybrid oligomers. their preparation process and pharmaceutical compositions containing them | CENTRE NAT RECH SCIENT (FR) | 2008-05-21 | — | — | CN | claimed |
| CN-1067216-C | Herbicidal compositions | RHONE POULENC AGROCHIMIE (FR) | 2001-06-20 | — | — | CN | claimed |
| US-5944887-A | Transformation of crude halogenated copper phthalocyanine pigments into a useful pigmentary state | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | claimed |
| CN-1038132-C | Prodn. method and use of 0,0-dialkyl-0-(2,4-dichloro-6-nitrophenyl) thiophasphate | SICHUAN CHEMICAL INDUSTRY RESE (CN) | 1998-04-22 | — | — | CN | claimed |
| CN-1089612-A | O, O-dialkyl group-O-(2,4-two chloro-6-nitrophenyls) phosphorothioate compound and method for making and purposes | SICHUAN PROV CHEMICAL INDUSTRY (CN) | 1994-07-20 | — | — | CN | claimed |
| CN-1083657-A | Herbicidal composition | RHONE POULENC AGROCHIMIE (FR) | 1994-03-16 | — | — | CN | claimed |
| EP-0299890-B1 | PROCESS FOR THE CHLORINATION OF PHENOLIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0283411-B1 | PROCESS FOR CHLORINATING PHENOLIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1991-08-07 | — | — | EP | claimed |
| US-4954662-A | Selective chlorination of ortho-substituted phenols | RHONE-POULENC CHIMIE (FR) | 1990-09-04 | — | — | US | claimed |
| EP-0284523-B1 | PROCESS FOR CHLORINATING NITROPHENOLS | RHONE-POULENC CHIMIE (FR) | 1990-07-11 | — | — | EP | claimed |
| EP-0362729-A1 | Process for producing water insoluble azo dyes on the fibre | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | claimed |
| US-4855513-A | Chlorination of phenolic compounds | RHONE-POULENC CHIMIE (FR) | 1989-08-08 | — | — | US | claimed |
| US-4827047-A | AMINE CATALYST | RHONE-POULENC CHIMIE (FR) | 1989-05-02 | — | — | US | claimed |
| JP-8245531-A | — | — | None | — | — | JP | disclosed |
| EP-4744661-A2 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| EP-4298092-B1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-11-26 | — | — | EP | disclosed |
| US-20250223307-A1 | MDM2/MDMX DOUBLE-TARGET INHIBITOR COMPOUND, PRODRUG, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | GLOBAL HEALTH DRUG DISCOVERY INSTITUTE (CN) | 2025-07-10 | — | — | US | disclosed |
| EP-4582420-A1 | MDM2/MDMX DOUBLE-TARGET INHIBITOR COMPOUND, PRODRUG, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Global Health Drug Discovery Institute (CN) | 2025-07-09 | — | — | EP | disclosed |
| EP-4554941-A1 | HERBICIDAL BENZOXAZINES | FMC Corporation (US) | 2025-05-21 | — | — | EP | disclosed |
| CN-119546601-A | Herbicidal benzoxazines | FMC公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119403533-A | Method for treating keratin fibres using a carnitine salt or a carnitine derivative | 莱雅公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-119403534-A | Method for treating keratin fibres comprising a pretreatment or post-treatment step | 莱雅公司 | 2025-02-07 | — | — | CN | disclosed |
| US-20240307362-A1 | 4H-PYRROLO[3,2-c]PYRIDIN-4-ONE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-09-19 | — | — | US | disclosed |
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2024-08-27 | — | — | US | disclosed |
| CN-118459382-A | Synthesis method of sulfhydryl phenyl ether compound | 上海泰初化工技术有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118063438-A | MDM2/MDMX double-target inhibitor compound, prodrug, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2024-05-24 | — | — | CN | disclosed |
| WO-2024104304-A1 | MDM2/MDMX DOUBLE-TARGET INHIBITOR COMPOUND, PRODRUG, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 北京华益健康药物研究中心 | 2024-05-23 | — | — | WO | disclosed |
| CN-118043027-A | Process for dyeing and/or lightening keratin fibres | 莱雅公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240109912-A1 | TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | JANSSEN PHARMACEUTICA NV (BY) | 2024-04-04 | — | — | US | disclosed |
| CN-117479916-A | Composition comprising at least one alkyl (poly) glycoside, at least one fatty alcohol, at least one fatty acid and at least one alkaline agent | 欧莱雅 | 2024-01-30 | — | — | CN | disclosed |
| US-20240025883-A1 | PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2024-01-25 | — | — | US | disclosed |
| WO-2024015425-A1 | HERBICIDAL BENZOXAZINES | FMC CORPORATION (US) | 2024-01-18 | — | — | WO | disclosed |
| EP-4298092-A1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| US-11820746-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2023-11-21 | — | — | US | disclosed |
| US-11820746-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2023-11-21 | — | — | US | disclosed |
| US-20230348384-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | UCB PHARMA GMBH (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230348384-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | UCB PHARMA GMBH (DE) | 2023-11-02 | — | — | US | disclosed |
| CN-116829550-A | Pyrimidine-2-ylsulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023180189-A1 | MPRO TARGETING ANTIVIRAL COMPOUNDS | EXSCIENTIA AI LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20230167074-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF, USE THEREOF, AND INTERMEDIATE THEREOF | FUJIFILM CORPORATION (JP) | 2023-06-01 | — | — | US | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |
| WO-2022180136-A1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-09-01 | — | — | WO | disclosed |
| US-11345662-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2022-05-31 | — | — | US | disclosed |
| US-20220127227-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | UCB PHARMA GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
| EP-3959212-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2022-03-02 | — | — | EP | disclosed |
| US-20220048858-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | UCB PHARMA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
| WO-2020216773-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |
| CN-110483492-A | Dipeptidyl peptidase i inhibitors | ASTRAZENECA AB | 2019-11-22 | — | — | CN | disclosed |
| US-20190345104-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | UCB PHARMA GMBH (DE) | 2019-11-14 | — | — | US | disclosed |
| EP-3562820-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB Pharma GmbH (DE) | 2019-11-06 | — | — | EP | disclosed |
| CN-106518845-B | Kynurenin -3- monooxygenase inhibitor, pharmaceutical composition and its application method | CHDI基金会股份有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-105980367-B | (2S) -N- [ (1S) -1-cyano-2-phenylethyl ] -1, 4-oxazepane-2-carboxamides as dipeptidyl peptidase I inhibitors | 阿斯利康(瑞典)有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110121499-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-110041201-A | A kind of preparation method of the chloro- 6- nitrophenol of oxyclozanide intermediate 2,4- bis- | 常州齐晖药业有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-110041201-A | A kind of preparation method of the chloro- 6- nitrophenol of oxyclozanide intermediate 2,4- bis- | 常州齐晖药业有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-110041201-A | A kind of preparation method of the chloro- 6- nitrophenol of oxyclozanide intermediate 2,4- bis- | 常州齐晖药业有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-104045552-B | Medicinal compound as neuroprotective agent | 江苏先声药业有限公司 | 2019-06-11 | — | — | CN | disclosed |
| EP-3080115-B1 | FUSED IMIDAZOLE AND PYRAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2019-05-08 | — | — | EP | disclosed |
| CN-105164104-B | Urea derivative and its purposes as fatty acid binding protein (FABP) inhibitor | 豪夫迈·罗氏有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-105916856-B | Substituted 4,5,6,7- tetrahydro-pyrazoles as Casein kinase 1 D/E inhibitor simultaneously [1,5-A] pyrazines derivatives | 百时美施贵宝公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-105814054-B | Condensed imidazole and pyrazole derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |
| CN-108059602-A | A kind of preparation method of oxyclozanide intermediate 2-amino -4,6- chlorophenesic acid organic solution | 常州齐晖药业有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-105621587-B | A kind of method using potentiometric titrations degradating chloro nitro-aromatic | 浙江大学 | 2018-01-23 | — | — | CN | disclosed |
| US-9868749-B2 | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB BIOPHARMA SPRL (BE) | 2018-01-16 | — | — | US | disclosed |
| CN-105431427-B | Novel PDE 4 inhibitor | 明治制果药业株式会社 | 2017-12-08 | — | — | CN | disclosed |
| CN-107074828-A | Compounds and compositions as raf kinase inhibitors | 诺华股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-105801444-B | The synthetic method of the carboxylic acid of 3 ' amino, 2 ' xenol 3 | 启东东岳药业有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-105085275-B | O-nitrophenol and its derivative synthesis method | 浙江工业大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-103957913-B | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof | CHDI FOUNDATION, INC. (US) | 2016-11-30 | — | — | CN | disclosed |
| EP-3080115-A1 | FUSED IMIDAZOLE AND PYRAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SPRL (BE) | 2016-10-19 | — | — | EP | disclosed |
| US-20160297837-A1 | Fused Imidazole and Pyrazole Derivatives As Modulators of TNF Activity | EVOTEC (UK) LTD. (GB) | 2016-10-13 | — | — | US | disclosed |
| CN-104262159-B | A kind of synthetic method of ortho-nitrophenyl phenolic compound | 浙江工业大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105801444-A | Synthesizing method for 3'-amino-2'-hydroxy biphenyl-3-carboxylic acid | 启东东岳药业有限公司 | 2016-07-27 | — | — | CN | disclosed |
| US-20160207938-A1 | QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-21 | — | — | US | disclosed |
| EP-1772493-B1 | AZO DYE | FUJIFILM CORP (JP) | 2016-07-20 | — | — | EP | disclosed |
| CN-105621587-A | Method for degrading chloro-nitroaromatic by using sulfate radicals | UNIV ZHEJIANG | 2016-06-01 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |
| US-9273013-B2 | Quinazoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-01 | — | — | US | disclosed |
| EP-1954287-B2 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2016-02-24 | — | — | EP | disclosed |
| CN-102718775-B | As the Macrocyclic quinazoline derivatives of antiproliferative | JANSSEN PHARMACEUTICA N.V. (BE) | 2016-02-17 | — | — | CN | disclosed |
| CN-105164104-A | Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors | HOFFMANN LA ROCHE | 2015-12-16 | — | — | CN | disclosed |
| CN-105085275-A | O-nitrophenol and its derivative synthesis method | UNIV ZHEJIANG TECHNOLOGY | 2015-11-25 | — | — | CN | disclosed |
| WO-2015086506-A1 | FUSED IMIDAZOLE AND PYRAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2015-06-18 | — | — | WO | disclosed |
| CN-102858742-B | Trpv1 vanilloid receptor antagonists with a bicyclic portion | PHARMESTE SRL | 2015-05-27 | — | — | CN | disclosed |
| CN-104592128-A | SUBSTITUTED CINNOLINE DERIVATIVES AS GABAA-RECEPTOR MODULATORS AND METHOD FOR THEIR SYNTHESIS | ASTRAZENECA AB | 2015-05-06 | — | — | CN | disclosed |
| CN-101119993-B | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARM INC | 2015-03-04 | — | — | CN | disclosed |
| CN-104262159-A | Synthesis method of o-nitrophenol compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-01-07 | — | — | CN | disclosed |
| US-8883826-B2 | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMA SA (CH) | 2014-11-11 | — | — | US | disclosed |
| CN-104045552-A | Medicinal compound as neuroprotective agent | SHANGHAI SIMCERE PHARMACEUTICAL RES CO LTD | 2014-09-17 | — | — | CN | disclosed |
| US-8674106-B2 | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMA SA (CH) | 2014-03-18 | — | — | US | disclosed |
| CN-101914028-B | Method for preparing 2-amido-4,6-dichlorophenol | UNIV CHANGZHOU | 2013-08-14 | — | — | CN | disclosed |
| US-20130178624-A1 | QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-07-11 | — | — | US | disclosed |
| US-20130178631-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2013-07-11 | — | — | US | disclosed |
| CN-102993084-A | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA | 2013-03-27 | — | — | CN | disclosed |
| US-8394786-B2 | Quinazoline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-03-12 | — | — | US | disclosed |
| US-8334290-B2 | CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2012-12-18 | — | — | US | disclosed |
| CN-101675018-B | 1,4-hydrogenation of sorbol with ru complexes | INNOVAROMA SA | 2012-12-05 | — | — | CN | disclosed |
| CN-101001846-B | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA | 2012-11-07 | — | — | CN | disclosed |
| US-20120277237-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2012-11-01 | — | — | US | disclosed |
| CN-101189203-B | Ortho-nitrosophenols as polymerization inhibitors | CHEMTURA CORP | 2012-10-10 | — | — | CN | disclosed |
| CN-102718775-A | Macrocyclic quinazoline derivatives as antiproliferative agents | JANSSEN PHARMACEUTICA NV | 2012-10-10 | — | — | CN | disclosed |
| CN-101018772-B | Neuroactive compounds | PRANA BIOTECHNOLOGY LTD | 2012-10-10 | — | — | CN | disclosed |
| EP-2426115-A2 | Alkynyl derivatives as modulators of metabotropic glutamate receptors | Addex Pharma SA (CH) | 2012-03-07 | — | — | EP | disclosed |
| EP-1633365-B1 | MACROCYCLIC QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2012-02-08 | — | — | EP | disclosed |
| US-8101637-B2 | Alkynyl derivatives as modulators of metatropic glutamate receptors | ADDEX PHARMA SA (CH) | 2012-01-24 | — | — | US | disclosed |
| CN-101072760-B | Malonamide derivatives as gamma-secretase inhibitors for the treatment of Alzheimer's disease | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-28 | — | — | CN | disclosed |
| EP-1954287-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110262658-A1 | PROCESS AND DEVICE FOR TREATING THE COATING OF THERMOPLASTIC RESIN CONTAINERS | ZOPPAS MATTEO | 2011-10-27 | — | — | US | disclosed |
| US-20110144331-A1 | Cinnoline Compounds for the Treatment of Anxiety, Cognitive and Mood Disorders | ASTRAZENECA AB (SE) | 2011-06-16 | — | — | US | disclosed |
| US-20110130552-A1 | AZO DYE | FUJIFILM CORPORATION (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110130552-A1 | AZO DYE | FUJIFILM CORPORATION (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110124849-A1 | AZO DYE | FUJIFILM CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20110124849-A1 | AZO DYE | FUJIFILM CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| US-7947815-B2 | Diazenyl isothiazolo[3,4-B]pyridines as dyes | FUJIFILM CORPORATION (JP) | 2011-05-24 | — | — | US | disclosed |
| US-7947815-B2 | Diazenyl isothiazolo[3,4-B]pyridines as dyes | FUJIFILM CORPORATION (JP) | 2011-05-24 | — | — | US | disclosed |
| EP-1828151-B1 | MALONAMIDE DERIVATIVES AS INHIBITORS OF GAMMA-SECRETASE FOR THE TREATMENT OF ALZHEIMER'S DISEASE | HOFFMANN LA ROCHE (CH) | 2011-04-06 | — | — | EP | disclosed |
| EP-2305687-A1 | Quinazoline derivatives | Janssen Pharmaceutica NV (BE) | 2011-04-06 | — | — | EP | disclosed |
| CN-101914028-A | Method for preparing 2-amido-4,6-dichlorophenol | UNIV CHANGZHOU | 2010-12-15 | — | — | CN | disclosed |
| CN-101891646-A | Preparation method of pentachlorohydrazide | CHANGZHOU YABANG QH PHARMACHEM CO LTD | 2010-11-24 | — | — | CN | disclosed |
| US-20100184738-A1 | Uses of cinnoline compounds to treat schizophrenia | ASTRAZENECA AB (SE) | 2010-07-22 | — | — | US | disclosed |
| US-20100105668-A1 | Quinazoline derivatives | FREYNE EDDY JEAN EDGARD | 2010-04-29 | — | — | US | disclosed |
| EP-2167091-A1 | CINNOLINE COMPOUNDS FOR USE IN THE TREATMENT OF SCHIZOPHRENIA | AstraZeneca AB (SE) | 2010-03-31 | — | — | EP | disclosed |
| CN-101675018-A | 1 of the sorbyl alcohol that carries out with ruthenium complex, 4-hydrogenation | INNOVAROMA SA | 2010-03-17 | — | — | CN | disclosed |
| US-7651538-B2 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | KAO CORPORATION (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7651538-B2 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | KAO CORPORATION (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7648975-B2 | Macrocyclic quinazoline derivatives as antiproliferative agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-01-19 | — | — | US | disclosed |
| US-20090264405-A1 | Cetp Inhibitors | MERCK SHARP & DOHME LLC | 2009-10-22 | — | — | US | disclosed |
| CN-101528235-A | Vegfr3 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2009-09-09 | — | — | CN | disclosed |
| EP-2077845-A2 | MACROCYCLIC QUINAZOLINE DERIVATIVES AS VEGFR3 INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-07-15 | — | — | EP | disclosed |
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2009-05-14 | — | — | US | disclosed |
| US-20090056038-A1 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | KAO CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090056038-A1 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | KAO CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| CN-101379042-A | Substituted cinnoline derivatives as GABAA receptor modulators and methods of synthesis thereof | ASTRAZENECA AB (SE) | 2009-03-04 | — | — | CN | disclosed |
| US-20090036454-A1 | Compounds and Uses Thereof | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | US | disclosed |
| US-20090018112-A1 | Compounds and Uses Thereof | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | US | disclosed |
| US-20080318925-A1 | Compounds and Uses Thereof - 849 | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| WO-2008155573-A1 | CINNOLINE COMPOUNDS FOR USE IN THE TREATMENT OF SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2008-12-24 | — | — | WO | disclosed |
| US-7465795-B2 | Compounds and uses thereof | ASTRAZENECA AB (SE) | 2008-12-16 | — | — | US | disclosed |
| CN-100441551-C | C-nitrosoaniline compounds and their blends as polymerization inhibitors | UNIROYAL CHEM CO INC (US) | 2008-12-10 | — | — | CN | disclosed |
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20080219975-A1 | VEGFR3 INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-09-11 | — | — | US | disclosed |
| EP-1966158-A1 | SUBSTITUTED CINNOLINE DERIVATIVES AS GABAA-RECEPTOR MODULATORS AND METHOD FOR THEIR SYNTHESIS | AstraZeneca AB (SE) | 2008-09-10 | — | — | EP | disclosed |
| EP-1954287-A2 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| CN-101242876-A | Oxidizing hair coloring agents containing m-aminophenol derivatives | PROCTER & GAMBLE (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-100402627-C | Quinone imine oxime compounds and blends thereof as polymerization inhibitors | UNIROYAL CHEMICAL CO LTD (US) | 2008-07-16 | — | — | CN | disclosed |
| CN-101189203-A | Ortho-nitrosophenols as polymerization inhibitors | CHEMTURA CORP (US) | 2008-05-28 | — | — | CN | disclosed |
| WO-2008049902-A2 | MACROCYCLIC QUINAZOLINE DERIVATIVES AS VEGFR3 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-05-02 | — | — | WO | disclosed |
| EP-1682076-A4 | INHIBITORS OF CORONAVIRUS PROTEASE AND METHODS OF USE THEREOF | FULCRUM PHARMACEUTICALS INC (US) | 2008-02-06 | — | — | EP | disclosed |
| CN-101119993-A | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| US-20080027221-A1 | Azo Dye | FUJIFILM CORPORATION (JP) | 2008-01-31 | — | — | US | disclosed |
| US-20080027221-A1 | Azo Dye | FUJIFILM CORPORATION (JP) | 2008-01-31 | — | — | US | disclosed |
| CN-100358859-C | Nitrofication method for catalysis of phenol and diphenyl ether compounds using metal salt | SHANGHAI ORGANICHEMISTRY INST (CN) | 2008-01-02 | — | — | CN | disclosed |
| CN-101072760-A | Malonamide derivatives as gamma-secretase inhibitors for the treatment of Alzheimer's disease | HOFFMANN LA ROCHE (CH) | 2007-11-14 | — | — | CN | disclosed |
| EP-1849454-A1 | HAIR DYE COMPOSITION | Kao Corporation (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1828151-A2 | MALONAMIDE DERIVATIVES AS INHIBITORS OF GAMMA-SECRETASE FOR THE TREATMENT OF ALZHEIMER'S DISEASE | F.HOFFMANN-LA ROCHE AG (CH) | 2007-09-05 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
| CN-101018772-A | Neuroactive compounds | PRANA BIOTECHNOLOGY LTD (AU) | 2007-08-15 | — | — | CN | disclosed |
| CN-101001846-A | Novel alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2007-07-18 | — | — | CN | disclosed |
| WO-2007073283-A1 | SUBSTITUTED CINNOLINE DERIVATIVES AS GABAA-RECEPTOR MODULATORS AND METHOD FOR THEIR SYNTHESIS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |
| US-20070142328-A1 | Compounds and Uses Thereof | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | US | disclosed |
| WO-2007070173-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070142382-A1 | Compounds and Uses Thereof | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | US | disclosed |
| US-7211573-B2 | Malonamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-05-01 | — | — | US | disclosed |
| EP-1772493-A1 | AZO DYE | Fujifilm Corporation (JP) | 2007-04-11 | — | — | EP | disclosed |
| EP-1765795-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2007-03-28 | — | — | EP | disclosed |
| US-7183267-B2 | β-lactamase inhibitors and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-02-27 | — | — | US | disclosed |
| US-20060247237-A1 | Macrocyclic quinazoline derivatives as antiproliferative agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-11-02 | — | — | US | disclosed |
| CN-1854115-A | C-nitrosoaniline compounds and their blends as polymerization inhibitors | UNIROYAL CHEM CO INC (US) | 2006-11-01 | — | — | CN | disclosed |
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | disclosed |
| EP-1682076-A2 | INHIBITORS OF CORONAVIRUS PROTEASE AND METHODS OF USE THEREOF | Fulcrum Pharmaceuticals, Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| CN-1794996-A | Macrocyclic quinazoline derivatives as antiproliferative agents | JANSSEN PHARMACEUTICA NV (BE) | 2006-06-28 | — | — | CN | disclosed |
| WO-2006061136-A2 | MALONAMIDE DERIVATIVES AS INHIBITORS OF GAMMA-SECRETASE FOR THE TREATMENT OF ALZHEIMER’S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-15 | — | — | WO | disclosed |
| US-20060122168-A1 | Malonamide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-08 | — | — | US | disclosed |
| EP-1635812-A2 | BETA-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF | Fulcrum Pharmaceuticals, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1633365-A1 | MACROCYCLIC QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-03-15 | — | — | EP | disclosed |
| CN-1740173-A | Interleukin-1 beta converting enzyme inhibitors | VERTEX PHARMA (US) | 2006-03-01 | — | — | CN | disclosed |
| EP-1385524-A4 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO KG (DE) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005123703-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-12-29 | — | — | WO | disclosed |
| US-20050282796-A1 | Tetracyclic azepinoindole compounds | PFIZER | 2005-12-22 | — | — | US | disclosed |
| CN-1709856-A | Nitrofication method for catalysis of phenol and diphenyl ether compounds using metal salt | SHANGHAI ORGANICHEMISTRY INST (CN) | 2005-12-21 | — | — | CN | disclosed |
| US-20050267071-A1 | Inhibitors of coronavirus protease and methods of use thereof | FULCRUM PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | US | disclosed |
| CN-1222551-C | Stable initiator system | JOHNSON & JOHNSON VISION CARE (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1222358-C | Catalyst comprising at least one phosphonite ligand based nickel (o) complex and method for the production of nitriles | BASF AG (DE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-6921763-B2 | Pyrazolopyrimidines as therapeutic agents | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| US-20050124580-A1 | Beta-lactamase inhibitors and methods of use thereof | FULCRUM PHARMACEUTICALS, INC. (US) | 2005-06-09 | — | — | US | disclosed |
| WO-2005041904-A2 | INHIBITORS OF CORONAVIRUS PROTEASE AND METHODS OF USE THEREOF | FULCRUM PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-6875762-B2 | Tetracyclic azepinoindole compounds | PFIZER (US) | 2005-04-05 | — | — | US | disclosed |
| WO-2005004799-A2 | β-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF | FULCRUM PHARMACEUTICALS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |
| CN-1183132-C | Tetracyclic azepinoindole compounds as 5-HT receptor ligands | �������Ŷ���Լ��������˾ | 2005-01-05 | — | — | CN | disclosed |
| WO-2004105765-A1 | MACROCYCLIC QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-12-09 | — | — | WO | disclosed |
| EP-1019190-B1 | CATALYST COMPRISING AT LEAST ONE PHOSPHONITE LIGAND BASED NICKEL (O) COMPLEX AND METHOD FOR THE PRODUCTION OF NITRILES | BASF AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-6794504-B2 | Chlorinated copper phthalocyanine pigments | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | disclosed |
| EP-1173440-B1 | TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS | UPJOHN CO (US) | 2004-09-15 | — | — | EP | disclosed |
| CN-1520298-A | Pyrazolopyrimidines as therapeutic agents | �����ʩ���عɷݹ�˾ | 2004-08-11 | — | — | CN | disclosed |
| CN-1159106-C | Catalyst comprising complex in metal from subgroup VIII based on bidentate phosphonite ligand, and method for producing nitriles | BASF公司 | 2004-07-28 | — | — | CN | disclosed |
| US-20040138202-A1 | Tetracyclic azepinoindole compounds | PHARMACIA AND UPJOHN COMPANY | 2004-07-15 | — | — | US | disclosed |
| CN-1500781-A | Inhibitors of interleukin-1 beta converting enzyme | ��̩��˹ҩ��ɷ�����˾ | 2004-06-02 | — | — | CN | disclosed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
| EP-1212327-B8 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO KG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-1385524-A1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | Abbott GmbH & Co. KG (DE) | 2004-02-04 | — | — | EP | disclosed |
| CN-1469916-A | C-nitrosoaniline compounds and blends thereof as polymerization inhibitors | �Ϻ���ͨ��ѧ | 2004-01-21 | — | — | CN | disclosed |
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1362843-A2 | N-cyclopropyl-2-difluoromethoxy-3-halogenoaniline and intermediate used for production thereof | Ihara Chemical Industry Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| CN-1127511-C | Inhibitors of interleukin-1 beta converting enzyme | VERTEX PHARMA (US) | 2003-11-12 | — | — | CN | disclosed |
| CN-1449391-A | N- (3, 5-dichloro-2-methoxyphenyl) -4-methoxy-3-piperazin-1-yl-benzenesulfonamide | SMITHKLINE BEECHAM PLC (GB) | 2003-10-15 | — | — | CN | disclosed |
| EP-1282666-B1 | CHLORINATED COPPER PHTHALOCYANINE PIGMENTS | BASF AG (DE) | 2003-09-24 | — | — | EP | disclosed |
| EP-1212327-B1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AG (DE) | 2003-08-20 | — | — | EP | disclosed |
| CN-1430629-A | Stable initiator system | JOHNSON & JOHNSON VISION CARE (US) | 2003-07-16 | — | — | CN | disclosed |
| US-20030088091-A1 | Chlorinated copper phthalocyanine pigments | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-08 | — | — | US | disclosed |
| US-6521778-B1 | Hydrocyanation of 1,3-butadiene to form adiponitrile | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-18 | — | — | US | disclosed |
| EP-1282666-A1 | CHLORINATED COPPER PHTHALOCYANINE PIGMENTS | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-20020198190-A1 | Tetracyclic azepinoindole compounds | PHARMACIA & UPJOHN COMPANY | 2002-12-26 | — | — | US | disclosed |
| US-20020156081-A1 | Pyrazolopyrimidines as therapeutic agents | ABBOTT LABORATORIES (US) | 2002-10-24 | — | — | US | disclosed |
| WO-2002080926-A1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO. KG (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-6407092-B1 | 5-HYDROXYTRYPTAMINE MODULATORS AND ANTISEROTONINE AGENTS; TREATING EATING, SEXUAL, SLEEP, NERVOUS SYSTEM, PSYCHOLOGICAL, AND GASTROINTESTINAL DISORDERS; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | PHARMACIA & UPJOHN COMPANY | 2002-06-18 | — | — | US | disclosed |
| EP-1212327-A2 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-12 | — | — | EP | disclosed |
| CN-1085232-C | Transformation of crude halogenated copper phthalocyanine pigments into useful pigmentary state | BASF AG (DE) | 2002-05-22 | — | — | CN | disclosed |
| CN-1348454-A | Tetracyclic azepinoindole compounds as 5-HT receptor ligands | UPJOHN CO (US) | 2002-05-08 | — | — | CN | disclosed |
| US-6355833-B2 | HYDROCYANATION OF BUTADIENE TO ADIPONITRILE | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | disclosed |
| EP-1091804-B1 | CATALYST COMPRISING A COMPLEX OF A METAL FROM SUBGROUP VIII BASED ON A BIDENTATE PHOSPHONITE LIGAND, AND METHOD FOR PRODUCING NITRILES | BASF AG (DE) | 2002-02-27 | — | — | EP | disclosed |
| EP-1173440-A1 | TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-23 | — | — | EP | disclosed |
| US-6316658-B1 | QUINOLONE CARBOXYLATE CHEMICAL INTERMEDIATES; MICROBIOCIDES, BACTERICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| WO-2001077231-A1 | CHLORINATED COPPER PHTHALOCYANINE PIGMENTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-18 | — | — | WO | disclosed |
| US-20010014647-A1 | Catalyst comprising at least one nickel(0) complex based on a phosphonite ligand, and the preparation of nitriles | FISCHER JAKOB (DE) | 2001-08-16 | — | — | US | disclosed |
| EP-0909795-B1 | Process to transfer crude halogenated copper-phthalocyanine pigments into a pigment form suitable for use | BASF AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| CN-1304334-A | Catalyst comprising a complex of a metal of subgroup VIII based on a bidentate phosphonite ligand and preparation of a nitrile | BASF AG (DE) | 2001-07-18 | — | — | CN | disclosed |
| US-6242633-B1 | Catalyst comprising at least one phosphonite ligand based nickel (O) complex and method for the production of nitriles | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | disclosed |
| EP-1091804-A1 | CATALYST COMPRISING A COMPLEX OF A METAL FROM SUBGROUP VIII BASED ON A BIDENTATE PHOSPHONITE LIGAND, AND METHOD FOR PRODUCING NITRILES | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-2001019829-A2 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
| US-6172268-B1 | REACTING A HYDROXY AROMATIC COMPOUND WITH A PROPYLENE OXIDE IN PRESENCE OF METAL COMPLEX CATALYST | ASAHI GLASS COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| WO-2000064899-A1 | TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-02 | — | — | WO | disclosed |
| CN-1270543-A | Catalyst comprising at least one phosphonite ligand-based nickel complex and production of nitriles | BASF AG (DE) | 2000-10-18 | — | — | CN | disclosed |
| EP-1031555-A1 | N-CYCLOPROPYL-2-DIFLUOROMETHOXY-3-HALOGENOANILINES AND INTERMEDIATES FOR THE PREPARATION THEREOF | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-1019190-A1 | CATALYST COMPRISING AT LEAST ONE PHOSPHONITE LIGAND BASED NICKEL (O) COMPLEX AND METHOD FOR THE PRODUCTION OF NITRILES | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999064155-A1 | CATALYST COMPRISING A COMPLEX OF A METAL FROM SUBGROUP VIII BASED ON A BIDENTATE PHOSPHONITE LIGAND, AND METHOD FOR PRODUCING NITRILES | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-16 | — | — | WO | disclosed |
| CN-1229412-A | Interleukin-1 beta converting enzyme inhibitors | VERTEX PHARMA (US) | 1999-09-22 | — | — | CN | disclosed |
| US-5944887-A | Transformation of crude halogenated copper phthalocyanine pigments into a useful pigmentary state | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| CN-1219558-A | Transformation of crude halogenated copper phthalocyanine pigments into useful pigmentary state | BASF AG (DE) | 1999-06-16 | — | — | CN | disclosed |
| EP-0909795-A1 | Process to transfer crude halogenated copper-phthalocyanine pigments into a pigment form suitable for use | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-21 | — | — | EP | disclosed |
| WO-1999013983-A1 | CATALYST COMPRISING AT LEAST ONE PHOSPHONITE LIGAND BASED NICKEL (O) COMPLEX AND METHOD FOR THE PRODUCTION OF NITRILES | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-25 | — | — | WO | disclosed |
| CN-1207743-A | Inhibitors of interleukin-1 beta converting enzyme | VERTEX PHARMA (US) | 1999-02-10 | — | — | CN | disclosed |
| US-5773651-A | Process for the preparation of fluorine-containing chemical compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| CN-1038132-C | Prodn. method and use of 0,0-dialkyl-0-(2,4-dichloro-6-nitrophenyl) thiophasphate | SICHUAN CHEMICAL INDUSTRY RESE (CN) | 1998-04-22 | — | — | CN | disclosed |
| EP-0778081-A1 | Process for preparing fluorine containing chemical compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-11 | — | — | EP | disclosed |
| JP-H08245531-A | PRODUCTION OF HALO-SUBSTITUTED AMINOPHENOL | DAINIPPON INK & CHEM INC | 1996-09-24 | — | — | JP | disclosed |
| EP-0596491-B1 | Method for halogenating an aromatic compound | ISHIHARA SANGYO KAISHA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5491239-A | Method for halogenating an aromatic compound | ISHIHARA SANGYO KAISHA LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| CN-1089612-A | O, O-dialkyl group-O-(2,4-two chloro-6-nitrophenyls) phosphorothioate compound and method for making and purposes | SICHUAN PROV CHEMICAL INDUSTRY (CN) | 1994-07-20 | — | — | CN | disclosed |
| EP-0596491-A1 | Method for halogenating an aromatic compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |
| EP-0393513-B1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | disclosed |
| EP-0325892-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED PRIMARY AMINES | CIBA-GEIGY AG (CH) | 1993-02-03 | — | — | EP | disclosed |
| CN-1062138-A | The synergy of HIV reverse transcriptase inhibitors | MERCK & CO INC (US) | 1992-06-24 | — | — | CN | disclosed |
| US-5105021-A | Reacting metal phenolate with (di)bromo(chloro)difluoromethane in presence of promoter | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0473552-A1 | Process for the preparation of halogenated aromatic primary amines | CIBA-GEIGY AG (CH) | 1992-03-04 | — | — | EP | disclosed |
| EP-0256504-B1 | PROCESS FOR THE EXTRACTION OF NITRO-HYDROXY-AROMATES FROM AQUEOUS SOLUTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-12-27 | — | — | EP | disclosed |
| EP-0393513-A1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-24 | — | — | EP | disclosed |
| CN-1009831-B | PROCESS FOR PREPARING HETEROCYCLE-OXO-2,3-DIAZANAPHTHYL-ACETIC ACID | PFIZER (US) | 1990-10-03 | — | — | CN | disclosed |
| US-4960936-A | Process for the preparation of halogenated aromatic primary amines | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4954662-A | Selective chlorination of ortho-substituted phenols | RHONE-POULENC CHIMIE (FR) | 1990-09-04 | — | — | US | disclosed |
| EP-0362729-A1 | Process for producing water insoluble azo dyes on the fibre | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | disclosed |
| US-4855513-A | Chlorination of phenolic compounds | RHONE-POULENC CHIMIE (FR) | 1989-08-08 | — | — | US | disclosed |
| EP-0325892-A2 | Process for the preparation of halogenated primary amines | CIBA-GEIGY AG (CH) | 1989-08-02 | — | — | EP | disclosed |
| US-4827047-A | AMINE CATALYST | RHONE-POULENC CHIMIE (FR) | 1989-05-02 | — | — | US | disclosed |
| US-4814518-A | SOLVENT EXTRACTION, AMINE SALTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |
| EP-0256504-A1 | Process for the extraction of nitro-hydroxy-aromates from aqueous solutions | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-24 | — | — | EP | disclosed |
| CN-86108308-A | Heterocycle oxo-2 guanidine-acetic acid | — | 1987-07-15 | — | — | CN | disclosed |
| EP-0011790-B1 | PROCESS FOR THE PREPARATION OF NITRODIPHENYL AMINE DERIVATIVES | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4238407-A | Process for the preparation of nitro diphenyl amine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| EP-0011790-A1 | Process for the preparation of nitrodiphenyl amine derivatives | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4180572-A | Lipogenesis control by esters of benzoxazinecarboxylic acids | SHELL OIL COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4146550-A | REACTION OF CARBAMIC ACID CHLORIDE WITH ACTIVE HYDROGEN COMPOUND, DECOMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
| US-4146550-A | REACTION OF CARBAMIC ACID CHLORIDE WITH ACTIVE HYDROGEN COMPOUND, DECOMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (40 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264405-A1 | Cetp Inhibitors | CETP, APOB, PCSK9 | GPR35 1627/4885ERN1 506/4885TDP1 860/4885 |
| US-20130178624-A1 | QUINAZOLINE DERIVATIVES | NR1H2, NR1H3, NR3C2 | GPR35 240/4885ERN1 3479/4885TDP1 4807/4885 |
| US-20050267071-A1 | Inhibitors of coronavirus protease and methods of use thereof | ACE, ACE2, CTRL | GPR35 4542/4885ERN1 513/4885TDP1 1427/4885 |
| US-20220127227-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | GPR17, GPR18, GPR27 | GPR35 5/4885ERN1 4584/4885TDP1 2989/4885 |
| US-20130178631-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | GRM5, GRM1, GRM2 | GPR35 36/4885ERN1 3764/4885TDP1 2938/4885 |
| US-11345662-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | GPR17, GPR18, GPR27 | GPR35 5/4885ERN1 4584/4885TDP1 2989/4885 |
| US-20050282796-A1 | Tetracyclic azepinoindole compounds | TBXA2R, NPY5R, AZI2 | GPR35 701/4885ERN1 3952/4885TDP1 1839/4885 |
| US-11820746-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | GPR17, GPR18, GPR27 | GPR35 5/4885ERN1 4584/4885TDP1 2989/4885 |
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | GRM5, GRM2, GRM1 | GPR35 37/4885ERN1 4114/4885TDP1 3469/4885 |
| US-20060247237-A1 | Macrocyclic quinazoline derivatives as antiproliferative agents | NR1H3, NR1H2, NCOA3 | GPR35 936/4885ERN1 3511/4885TDP1 4789/4885 |
| US-20070142328-A1 | Compounds and Uses Thereof | MAPT, BDNF, PYGB | GPR35 1191/4885ERN1 3743/4885TDP1 194/4885 |
| US-20220048858-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | GPR17, GPR18, GPR27 | GPR35 5/4885ERN1 4584/4885TDP1 2989/4885 |
| US-20230348384-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | GPR17, GPR18, GPR27 | GPR35 5/4885ERN1 4584/4885TDP1 2989/4885 |
| US-20240307362-A1 | 4H-PYRROLO[3,2-c]PYRIDIN-4-ONE COMPOUNDS | CYP4B1, CYP2C19, CYP3A4 | GPR35 3962/4885ERN1 4514/4885TDP1 2655/4885 |
| US-20070142382-A1 | Compounds and Uses Thereof | MAPT, BDNF, PYGB | GPR35 1191/4885ERN1 3743/4885TDP1 194/4885 |
| US-20230167074-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF, USE THEREOF, AND INTERMEDIATE THEREOF | DHRS9, DHODH, CBR1 | GPR35 2922/4885ERN1 1711/4885TDP1 3926/4885 |
| US-20110144331-A1 | Cinnoline Compounds for the Treatment of Anxiety, Cognitive and Mood Disorders | HTR7, HTR2C, CRH | GPR35 852/4885ERN1 3421/4885TDP1 302/4885 |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | GPR35 3372/4885ERN1 4367/4885TDP1 4391/4885 |
| US-20120277237-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | GRM5, GRM1, GRM2 | GPR35 36/4885ERN1 3764/4885TDP1 2938/4885 |
| US-20100105668-A1 | Quinazoline derivatives | NR1H2, NR1H3, NR3C2 | GPR35 247/4885ERN1 3399/4885TDP1 4805/4885 |
| US-20240025883-A1 | PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | GPR17, GPR27, GPR119 | GPR35 15/4885ERN1 4079/4885TDP1 3673/4885 |
| US-20240109912-A1 | TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | CDK7, CDK2, CCNK | GPR35 2264/4885ERN1 878/4885TDP1 831/4885 |
| US-20080219975-A1 | VEGFR3 INHIBITORS | FLT4, FLT1, KDR | GPR35 1132/4885ERN1 3928/4885TDP1 4087/4885 |
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | GPR17, GPR18, GPR27 | GPR35 5/4885ERN1 4584/4885TDP1 2989/4885 |
| US-20090018112-A1 | Compounds and Uses Thereof | MAPT, BDNF, PYGB | GPR35 1191/4885ERN1 3743/4885TDP1 194/4885 |
| US-20040138202-A1 | Tetracyclic azepinoindole compounds | TPH1, AZI2, CYP1A2 | GPR35 716/4885ERN1 2623/4885TDP1 881/4885 |
| US-20190345104-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | GPR17, GPR18, GPR27 | GPR35 5/4885ERN1 4584/4885TDP1 2989/4885 |
| US-20020198190-A1 | Tetracyclic azepinoindole compounds | TPH1, AZI2, CYP1A2 | GPR35 716/4885ERN1 2623/4885TDP1 881/4885 |
| US-20160207938-A1 | QUINAZOLINE DERIVATIVES | NR1H2, NR1H3, NR3C2 | GPR35 467/4885ERN1 3563/4885TDP1 4802/4885 |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | GPR35 1351/4885ERN1 3192/4885TDP1 2928/4885 |
| US-20160297837-A1 | Fused Imidazole and Pyrazole Derivatives As Modulators of TNF Activity | TNF, TNFRSF1A, TNFRSF9 | GPR35 1405/4885ERN1 1525/4885TDP1 225/4885 |
| US-20090056038-A1 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | SCO2, IK, AR | GPR35 1683/4885ERN1 3987/4885TDP1 1912/4885 |
| US-20080027221-A1 | Azo Dye | IK, ACMSD, ARG1 | GPR35 3134/4885ERN1 2765/4885TDP1 3752/4885 |
| US-20250223307-A1 | MDM2/MDMX DOUBLE-TARGET INHIBITOR COMPOUND, PRODRUG, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | MDM2, TP53, TP53BP1 | GPR35 2207/4885ERN1 3556/4885TDP1 1237/4885 |
| US-20090036454-A1 | Compounds and Uses Thereof | MAPT, BDNF, PYGB | GPR35 1191/4885ERN1 3743/4885TDP1 194/4885 |
| US-20020156081-A1 | Pyrazolopyrimidines as therapeutic agents | DPYD, CYP2D6, UGT1A1 | GPR35 1419/4885ERN1 2452/4885TDP1 262/4885 |
| US-20050124580-A1 | Beta-lactamase inhibitors and methods of use thereof | LCT, BCHE, GAA | GPR35 4030/4885ERN1 1830/4885TDP1 2205/4885 |
| US-20100184738-A1 | Uses of cinnoline compounds to treat schizophrenia | COMT, BACE1, CHAT | GPR35 424/4885ERN1 4095/4885TDP1 1394/4885 |
| US-20060122168-A1 | Malonamide derivatives | ACE, REN, ME1 | GPR35 776/4885ERN1 1013/4885TDP1 1399/4885 |
| US-20080318925-A1 | Compounds and Uses Thereof - 849 | COMT, UGT1A9, BACE1 | GPR35 596/4885ERN1 3592/4885TDP1 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.