Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31637162 | 0.81 | S1PR4 (0.32) | S1PR4PDGFRBPDGFRA | |
| SCHEMBL4316318 | 0.73 | MET (0.51) | — | |
| SCHEMBL31317412 | 0.73 | ALDH1A1 (0.32) | S1PR4 | |
| SCHEMBL28815861 | 0.73 | S1PR4 (0.40) | S1PR4PDGFRBPDGFRA | |
| SCHEMBL10780332 | 0.73 | PDGFRB (0.34) | PDGFRBPDGFRA | |
| SCHEMBL31637142 | 0.71 | PLAU (0.34) | PDGFRBPDGFRA | |
| SCHEMBL266083 | 0.67 | — | — | |
| SCHEMBL29628445 | 0.67 | S1PR4 (0.33) | S1PR4 | |
| SCHEMBL23726300 | 0.67 | PARP1 (0.36) | PDGFRBPDGFRA | |
| SCHEMBL7157574 | 0.66 | PDGFRB (0.59) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206734-A1 | BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS | INCYTE CORPORATION | 2025-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206734-A1 | BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS | MRGPRX2, MRGPRX1, MRGPRX4 | S1PR4 410/4885PDGFRB 740/4885PDGFRA 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.