Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 6/20 | 0.41 |
| ▸ | HTR1B | P28222 | 5/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982763 | 0.76 | NISCH (0.56) | NISCHTAAR1HTR1DHTR1BADRA1A | |
| SCHEMBL10777341 | 0.68 | NISCH (0.60) | NISCHHTR1DHTR1BADRA1AADRA2A | |
| Tymazoline SCHEMBL29387735 | 0.68 | NISCH (0.70) | NISCHTAAR1ADRA1AADRA2AADRA2B | |
| Tymazoline SCHEMBL250491 | 0.68 | NISCH (0.70) | NISCHTAAR1ADRA1AADRA2AADRA2B | |
| SCHEMBL3962998 | 0.67 | NISCH (0.74) | NISCHADRA1AADRA2AADRA2BADRA2C | |
| Tymazoline SCHEMBL4415590 | 0.67 | NISCH (0.68) | NISCHTAAR1ADRA1AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL9654911 | 0.66 | NISCH (0.72) | NISCHADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL3169446 | 0.66 | HTR1D (0.61) | NISCHHTR1DHTR1BADRA1AADRA2A | |
| Fenoxazoline SCHEMBL193061 | 0.65 | NISCH (1.00) | NISCHTAAR1ADRA1AADRA2AADRA2B | |
| Fenoxazoline SCHEMBL317133 | 0.64 | NISCH (0.97) | NISCHTAAR1ADRA1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086428-B1 | ANTIDIARRHOEA VETERINARY COMPOSITION, ITS PRODUCTION AND ORAL DOSER CONTAINING IT | BEECHAM GROUP PLC (GB) | 1987-07-29 | — | — | EP | disclosed |