Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tymazoline SCHEMBL250491 | 0.87 | NISCH (0.70) | NISCHTAAR1ADRA1AADRA1DADRA1B | |
| Tymazoline SCHEMBL29387735 | 0.87 | NISCH (0.70) | NISCHTAAR1ADRA1AADRA1DADRA1B | |
| Tymazoline SCHEMBL4415590 | 0.86 | NISCH (0.68) | NISCHTAAR1ADRA1AADRA1DADRA1B | |
| Tymazoline SCHEMBL28142132 | 0.82 | NISCH (0.81) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| SCHEMBL10782839 | 0.76 | NISCH (0.48) | NISCHTAAR1ADRA1AADRA1DADRA1B | |
| Fenoxazoline SCHEMBL193061 | 0.72 | NISCH (1.00) | NISCHTAAR1ADRA1AADRA1DADRA1B | |
| SCHEMBL11265817 | 0.71 | NISCH (0.58) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| Fenoxazoline SCHEMBL317133 | 0.71 | NISCH (0.97) | NISCHTAAR1ADRA1AADRA1DADRA1B | |
| Fenoxazoline SCHEMBL1650113 | 0.71 | NISCH (0.97) | NISCHADRA1AADRA1DADRA1BADRA2A | |
| SCHEMBL9463062 | 0.71 | LMNA (0.54) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0692975-A4 | ADMINISTRATION OF VASO-ACTIVE AGENT AND THERAPEUTIC AGENT | UNIV QUEENSLAND (AU) | 2000-11-29 | — | — | EP | disclosed |
| US-5750141-A | DRUG DELIVERY TO BODY TISSUE BELOW THE STRATUM CORNEUM AND INCREASE LOCAL PERFUSION AND/OR CONCENTRATION OF THE DRUG | THE UNIVERSITY OF QUEENSLAND (AU) | 1998-05-12 | — | — | US | disclosed |
| EP-0692975-A1 | ADMINISTRATION OF VASO-ACTIVE AGENT AND THERAPEUTIC AGENT | THE UNIVERSITY OF QUEENSLAND (AU) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994023748-A1 | ADMINISTRATION OF VASO-ACTIVE AGENT AND THERAPEUTIC AGENT | THE UNIVERSITY OF QUEENSLAND (AU) | 1994-10-27 | — | — | WO | disclosed |
| US-5334138-A | Drug delivery; mixture of active material and vasoconstrictor | NORTH CAROLINA STATE UNIVERSITY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0448299-B1 | Composition for increased skin concentration of active agents by iontophoresis | BECTON DICKINSON CO (US) | 1994-06-01 | — | — | EP | disclosed |
| EP-0448299-A2 | Composition for increased skin concentration of active agents by iontophoresis | Becton, Dickinson and Company (US) | 1991-09-25 | — | — | EP | disclosed |