Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783579 | 0.86 | KMT2A (0.37) | MAPTCTSDTUBB4ATUBBTUBA3C | |
| SCHEMBL10786151 | 0.82 | TUBB4A (0.43) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10785705 | 0.75 | CTSD (0.47) | CTSDTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14421959 | 0.74 | MAOA (0.54) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10782696 | 0.73 | NPC1 (0.42) | MAPTCTSDTUBB4ATUBBTUBA3C | |
| SCHEMBL10785976 | 0.70 | SMN1; SMN2 (0.37) | MAPTNPC1KMT2ALMNAALDH1A1 | |
| SCHEMBL10786441 | 0.69 | TUBB1 (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10786018 | 0.69 | POLB (0.43) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10785850 | 0.69 | ABCB11 (0.48) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10786590 | 0.69 | SMN1; SMN2 (0.42) | MAPTTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |