Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620674 | 0.88 | HTR2A (0.44) | ALDH1A1CYP3A4ATM | |
| SCHEMBL27922683 | 0.84 | NOS3 (0.41) | ALDH1A1ATMNPC1RAB9AAR | |
| SCHEMBL10784877 | 0.80 | KIF11 (0.57) | ESR1ESR2KIF11CYP3A4P4HB | |
| SCHEMBL10785834 | 0.80 | LMNA (0.46) | MAOBMAPTAR | |
| SCHEMBL10356748 | 0.80 | ESR1 (0.36) | ESR1ESR2KIF11BACE1ATM | |
| SCHEMBL10740520 | 0.79 | MEN1 (0.46) | ESR1ESR2ALDH1A1CYP3A4ATM | |
| SCHEMBL10598204 | 0.78 | ESR1 (0.57) | ESR1ESR2KIF11ALDH1A1CYP3A4 | |
| SCHEMBL7809644 | 0.78 | SMN1; SMN2 (0.47) | CYP3A4 | |
| SCHEMBL19843843 | 0.78 | ESR1 (0.62) | ESR1ESR2ALDH1A1CYP3A4ABCG2 | |
| SCHEMBL10740804 | 0.75 | ESR1 (0.47) | ESR1ESR2KIF11ALDH1A1P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112588-B1 | 4-HYDROXY-ALPHA-ETHYL BENZHYDROLES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-11-11 | — | — | EP | claimed |
| US-4508926-A | FOR TREATMENT OF ACUTE ETHANOLIC INTOXICATION | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-04-02 | — | — | US | claimed |
| US-4508926-A | FOR TREATMENT OF ACUTE ETHANOLIC INTOXICATION | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-04-02 | — | — | US | disclosed |