Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21659085 | 1.00 | LMNA (0.50) | LMNATP53EPHX2FAAHS1PR2 | |
| SCHEMBL27915805 | 0.92 | LMNA (0.50) | LMNATP53EPHX2FAAHS1PR2 | |
| SCHEMBL27000192 | 0.92 | TP53 (0.48) | LMNATP53EPHX2FAAHS1PR2 | |
| SCHEMBL503545 | 0.90 | LMNA (0.48) | LMNATP53EPHX2FAAHS1PR2 | |
| SCHEMBL28414215 | 0.88 | TP53 (0.50) | LMNATP53EPHX2FAAHS1PR2 | |
| SCHEMBL29002121 | 0.87 | ALDH1A1 (0.43) | LMNATP53EPHX2S1PR2S1PR1 | |
| SCHEMBL496699 | 0.87 | FAAH (0.56) | EPHX2FAAHCA2 | |
| SCHEMBL22200 | 0.87 | FAAH (0.56) | EPHX2FAAHCA2 | |
| SCHEMBL304724 | 0.87 | FAAH (0.56) | EPHX2FAAHCA2 | |
| SCHEMBL22608765 | 0.87 | FAAH (0.56) | EPHX2FAAHCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647387-A | Succinic anhydride promoter overbased magnesium sulfonates and oils containing same | WITCO CHEMICAL CORP. (US) | 1987-03-03 | — | — | US | disclosed |
| US-4617135-A | BENZOIIC ACID DERIVATIVES AS PROMOTERS | WITCO CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |