Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784866 | 0.81 | CTSL (0.70) | CTSKPSMB5CTSLCTSBCTSS | |
| SCHEMBL7464745 | 0.80 | CTSK (0.71) | CTSKPSMB5SCN9ACNR2CTSL | |
| SCHEMBL7560380 | 0.78 | CTSK (0.49) | CTSKPSMB5SCN9ACNR2CTSL | |
| SCHEMBL10782255 | 0.78 | CTSL (0.52) | CTSKSCN9ACTSLCTSBCTSS | |
| SCHEMBL10784918 | 0.76 | HSPA5 (0.61) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7463889 | 0.76 | CTSL (0.49) | CTSKPSMB5SCN9ACNR2CTSL | |
| SCHEMBL7651598 | 0.76 | CTSK (0.50) | CTSKPSMB5SCN9ACNR2CTSL | |
| SCHEMBL7248005 | 0.75 | CTSK (0.59) | CTSKPSMB5SCN9ACTSSKDM4E | |
| SCHEMBL7468216 | 0.75 | CTSK (0.53) | CTSKPSMB5SCN9ACNR2CTSL | |
| SCHEMBL10782355 | 0.75 | CTSL (0.53) | CTSKCTSLCTSBCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099056-B1 | N-ACYL DERIVATIVES OF DIPEPTIDES, THEIR MANUFACTURE AND USE IN TREATING DISEASES, AND MEANS THEREFOR | BASF Aktiengesellschaft (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4610818-A | N-acyl derivatives of dipeptides, their preparation and their use in the therapy of disorders, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0099056-A2 | N-acyl derivatives of dipeptides, their manufacture and use in treating diseases, and means therefor | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | disclosed |