Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 6/20 | 0.61 |
| ▸ | HSPA2 | P54652 | 3/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784866 | 0.81 | CTSL (0.70) | CTSKCTSBCTSSCTSL | |
| SCHEMBL10780117 | 0.79 | CTSL (0.48) | HSPA5HSPA2CTSKCTSBCTSS | |
| SCHEMBL5717751 | 0.78 | KDM4E (0.64) | RAB9AHPGDTSHR | |
| SCHEMBL21514802 | 0.77 | HSPA5 (0.40) | HSPA5HSPA2CTSKCTSBCTSS | |
| SCHEMBL10782355 | 0.77 | CTSL (0.53) | CTSKCTSBCTSSCTSLTSHR | |
| SCHEMBL10779891 | 0.77 | KISS1R (0.46) | CTSKCTSBCTSSCTSL | |
| SCHEMBL23818887 | 0.76 | HSPA5 (1.00) | HSPA5HSPA2CTSKHSPA9TSHR | |
| SCHEMBL10784901 | 0.76 | CTSK (0.56) | CTSKCTSBCTSSCTSL | |
| SCHEMBL10782255 | 0.75 | CTSL (0.52) | CTSKCTSBCTSSCTSL | |
| SCHEMBL8865514 | 0.74 | RAB9A (0.58) | HSPA5HSPA2CTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099056-B1 | N-ACYL DERIVATIVES OF DIPEPTIDES, THEIR MANUFACTURE AND USE IN TREATING DISEASES, AND MEANS THEREFOR | BASF Aktiengesellschaft (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4610818-A | N-acyl derivatives of dipeptides, their preparation and their use in the therapy of disorders, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0099056-A2 | N-acyl derivatives of dipeptides, their manufacture and use in treating diseases, and means therefor | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | disclosed |