Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784866 | 0.85 | CTSL (0.70) | CTSLCTSBCTSSCTSK | |
| SCHEMBL9828179 | 0.81 | LMNA (0.57) | CTSLCTSBCTSSCTSKSCN9A | |
| SCHEMBL2228194 | 0.81 | LMNA (0.57) | CTSLCTSBCTSSCTSKSCN9A | |
| SCHEMBL2227252 | 0.79 | TAS1R3 (0.61) | SCN9ALMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1687071 | 0.78 | THRB (0.73) | THRBLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10784901 | 0.78 | CTSK (0.56) | CTSLCTSBCTSSCTSKSCN9A | |
| SCHEMBL5553285 | 0.77 | LMNA (0.65) | THRBLMNAADAM17ALDH1A1MEN1 | |
| SCHEMBL8006880 | 0.76 | ERAP2 (0.52) | CTSLCTSBCTSSCTSKSCN9A | |
| SCHEMBL10780117 | 0.76 | CTSL (0.48) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6184185 | 0.75 | CTSL (0.53) | CTSLCTSBCTSSCTSKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099056-B1 | N-ACYL DERIVATIVES OF DIPEPTIDES, THEIR MANUFACTURE AND USE IN TREATING DISEASES, AND MEANS THEREFOR | BASF Aktiengesellschaft (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4610818-A | N-acyl derivatives of dipeptides, their preparation and their use in the therapy of disorders, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0099056-A2 | N-acyl derivatives of dipeptides, their manufacture and use in treating diseases, and means therefor | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | disclosed |