Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL10782885 | 0.98 | TSHR (0.41) | LMNATSHRNFKB1PMP22GPR84 | |
| Succinic Acid SCHEMBL10783771 | 0.93 | LMNA (0.38) | LMNAOR51E2 | |
| SCHEMBL1142231 | 0.89 | CD81 (0.31) | TSHRALDH1A1 | |
| Malonic Acid SCHEMBL10783258 | 0.85 | LDHA (0.35) | — | |
| SCHEMBL28431090 | 0.85 | CD81 (0.31) | TSHRALDH1A1 | |
| SCHEMBL10346801 | 0.81 | CD81 (0.30) | — | |
| Sebacic Acid SCHEMBL10785950 | 0.81 | LMNA (0.39) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL2537050 | 0.79 | — | — | |
| Glutarate SCHEMBL10786171 | 0.79 | FNTA (0.38) | LMNATSHRPPARGPPARDPPARA | |
| Itaconate SCHEMBL10783955 | 0.78 | ALOX15 (0.46) | ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102830-B1 | DELUSTERING COATING COMPOSITION EXCELLENT IN ABRASION RESISTANCE | MITSUBISHI RAYON CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |
| US-4518472-A | COMPOUND CONTAINING AT LEAST THREE (METH)ACRYLOYLOXY GROUPS, PHOTOSENSITIZER, EMULSION-TYPE CROSSLINKED POLYMER | MITSUBISHI RAYON COMPANY LTD. (JP) | 1985-05-21 | — | — | US | disclosed |
| EP-0102830-A2 | Delustering coating composition excellent in abrasion resistance | MITSUBISHI RAYON CO., LTD. (JP) | 1984-03-14 | — | — | EP | disclosed |