Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | S100B | P04271 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318486 | 0.92 | KDM4E (0.35) | KDM4EHTTMAPT | |
| SCHEMBL10787625 | 0.85 | ALDH1A1 (0.36) | HTTMAPTGAAALDH1A1 | |
| SCHEMBL10784122 | 0.80 | S100B (0.38) | KDM4EHTTMAPTS100BTDP1 | |
| SCHEMBL11323978 | 0.79 | MAPT (0.35) | KDM4EHTTMAPTGAAALDH1A1 | |
| Acetic Acid SCHEMBL11810691 | 0.74 | MAPT (0.36) | KDM4EHTTMAPTGAA | |
| SCHEMBL11783316 | 0.73 | TDP1 (0.31) | TDP1 | |
| SCHEMBL11316324 | 0.73 | TP53 (0.33) | TDP1 | |
| SCHEMBL10784128 | 0.72 | NPC1 (0.36) | MAPTTDP1ALDH1A1LMNAPKM | |
| SCHEMBL11414969 | 0.71 | MAPT (0.36) | KDM4EMAPTTDP1GAAALDH1A1 | |
| SCHEMBL10783938 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675130-A | HAIR DYES | L'OREAL (FR) | 1987-06-23 | — | — | US | disclosed |