SCHEMBL1078656

SCHEMBL1078656

CC1(C)OCC(CCBr)O1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.44
ALDH1A1 P00352 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM3 P20309 1/20 0.34
TMEM97 Q5BJF2 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10314733 1.00 CA2 (0.44) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL4402227 1.00 CA2 (0.44) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL31370603 0.88 CA2 (0.42) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL7154999 0.86 CA2 (0.50) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL18817541 0.86 CA2 (0.50) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL11190794 0.86 CA2 (0.41) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL22841212 0.84 CA2 (0.40) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL10810001 0.84 CA2 (0.40) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL31362250 0.84 CA2 (0.40) CA2ALDH1A1NPSR1CHRM2CHRM4
SCHEMBL935836 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250249131-A1 SACCHARIDE-BASED MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-08-07 US disclosed
US-20240316206-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-09-26 US disclosed
US-12016929-B2 Lipid formulations for delivery of therapeutic agents ARBUTUS BIOPHARMA CORPORATION (CA) 2024-06-25 US disclosed
US-12016929-B2 Lipid formulations for delivery of therapeutic agents ARBUTUS BIOPHARMA CORPORATION (CA) 2024-06-25 US disclosed
US-20240150298-A1 ANTIBACTERIAL COMPOUNDS BLACKSMITH MEDICINES, INC. 2024-05-09 US disclosed
US-20240148875-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-05-09 US disclosed
US-20240100166-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-03-28 US disclosed
EP-4294792-A1 ANTIBACTERIAL COMPOUNDS Blacksmith Medicines, Inc. (US) 2023-12-27 EP disclosed
CN-117279898-A Antibacterial compounds 布莱克史密斯医药公司 2023-12-22 CN disclosed
US-11786598-B2 Lipid formulations for delivery of therapeutic agents ARBUTUS BIOPHARMA CORPORATION (CA) 2023-10-17 US disclosed
WO-2011000107-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS TO SOLID TUMORS PROTIVA BIOTHERAPEUTICS, INC. (CA) 2011-01-06 WO disclosed
WO-2011000107-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS TO SOLID TUMORS PROTIVA BIOTHERAPEUTICS, INC. (CA) 2011-01-06 WO disclosed
WO-2011000106-A1 IMPROVED CATIONIC LIPIDS AND METHODS FOR THE DELIVERY OF THERAPEUTIC AGENTS PROTIVA BIOTHERAPEUTICS, INC. (CA) 2011-01-06 WO disclosed
US-7456169-B2 Heterocyclic kinase inhibitors ABBOTT LABORATORIES INC. (US) 2008-11-25 US disclosed
CN-101080408-A Trycyclic heterocycles, their manufacture and use as pharmaceutical agents HOFFMANN LA ROCHE (CH) 2007-11-28 CN disclosed
US-20070254867-A1 Heterocyclic Kinase Inhibitors ABBVIE INC. 2007-11-01 US disclosed
CN-1069633-C Iodo-substituted X-ray contrast agents NYCOMED IMAGING AS (NO) 2001-08-15 CN disclosed
CN-1166826-A Iodo-substituted X-ray contrast agents NYCOMED IMAGING AS (NO) 1997-12-03 CN disclosed
US-4882402-A Side chain liquid crystalline polymeric media exhibiting third order nonlinear optical response HOECHST CELANESE CORPORATION (US) 1989-11-21 US disclosed
EP-0260127-A2 Xanthine derivatives, their preparation and pharmaceutical compositions containing them BEECHAM - WUELFING GmbH & Co. KG (DE) 1988-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240100166-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS PNLIP, NPC1L1, CETP CA2 3725/4885ALDH1A1 2161/4885NPSR1 2165/4885
US-20240148875-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS PNLIP, NPC1L1, CETP CA2 3725/4885ALDH1A1 2161/4885NPSR1 2165/4885
US-20250249131-A1 SACCHARIDE-BASED MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME CD44, ALG1, CSGALNACT1 CA2 2570/4885ALDH1A1 733/4885NPSR1 2973/4885
US-20240316206-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS PNLIP, NPC1L1, CETP CA2 3725/4885ALDH1A1 2161/4885NPSR1 2165/4885
US-20240150298-A1 ANTIBACTERIAL COMPOUNDS MRPL21, MPO, RPN2 CA2 4443/4885ALDH1A1 4166/4885NPSR1 4240/4885
US-11786598-B2 Lipid formulations for delivery of therapeutic agents CETP, PNLIP, NPC1L1 CA2 3625/4885ALDH1A1 1878/4885NPSR1 2451/4885
US-20070254867-A1 Heterocyclic Kinase Inhibitors MAP3K20, MAP3K19, MAP4K2 CA2 3100/4885ALDH1A1 3257/4885NPSR1 4065/4885
US-12016929-B2 Lipid formulations for delivery of therapeutic agents CETP, PNLIP, NPC1L1 CA2 3625/4885ALDH1A1 1878/4885NPSR1 2451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.