Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | VDR | P11473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567449 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KMT2AGAAALOX15TP53 | |
| SCHEMBL10786785 | 0.77 | POLB (0.43) | ALDH1A1KMT2AGAATP53HPGD | |
| SCHEMBL11583134 | 0.76 | CYP3A4 (0.61) | ALDH1A1KMT2AGAALMNAMAPT | |
| SCHEMBL15934239 | 0.76 | CYP3A4 (0.55) | ALDH1A1KMT2AGAAALOX15TP53 | |
| SCHEMBL7571211 | 0.73 | KDM4E (0.39) | ALDH1A1KMT2AGAAALOX15TP53 | |
| SCHEMBL4572861 | 0.73 | MAPT (0.55) | ALDH1A1KMT2AGAAHPGDMAPK1 | |
| SCHEMBL15934241 | 0.73 | IDO1 (0.47) | ALDH1A1GAATP53MAPK1VDR | |
| SCHEMBL6836535 | 0.72 | CXCR2 (0.46) | ALDH1A1KMT2AGAAALOX15TP53 | |
| SCHEMBL15934307 | 0.71 | IDO1 (0.49) | ALDH1A1GAATP53HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL9313034 | 0.71 | CXCR2 (0.45) | ALDH1A1KMT2AGAAALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035422-A | DYEING | L'OREAL (FR) | 1977-07-12 | — | — | US | claimed |
| US-4035422-A | DYEING | L'OREAL (FR) | 1977-07-12 | — | — | US | disclosed |