Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.60 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.60 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.60 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.52 |
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18612829 | 0.86 | NPC1 (0.54) | CNR2LMNAHTTPDK1PDK2 | |
| SCHEMBL4922162 | 0.82 | EPHX2 (0.81) | CNR2HTTEPHX2CNR1RAB9A | |
| SCHEMBL1464344 | 0.80 | CNR2 (1.00) | CNR2LMNAHTTPDK1PDK2 | |
| SCHEMBL3736169 | 0.80 | L3MBTL1 (0.73) | CNR2LMNAHTTPDK1PDK2 | |
| SCHEMBL28910371 | 0.79 | TRPV1 (0.71) | TRPV1NPC1RAB9ASMN1; SMN2P2RX1 | |
| SCHEMBL8407102 | 0.78 | LMNA (0.66) | CNR2LMNAHTTPDK1PDK2 | |
| SCHEMBL11874552 | 0.77 | LMNA (0.64) | CNR2LMNAHTTPDK1PDK2 | |
| SCHEMBL3959053 | 0.76 | HTT (1.00) | CNR2LMNAHTTPDK1PDK2 | |
| SCHEMBL20870704 | 0.76 | EPHX2 (0.70) | LMNAHTTEPHX2TRPV1NPC1 | |
| SCHEMBL5550330 | 0.76 | HDAC1 (0.67) | CNR2LMNAPDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146025-B1 | ALPHA,ALPHA-DIMETHYLPHENYLACETANILIDE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS INSECTICIDE | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1987-01-14 | — | — | EP | claimed |