Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784246 | 0.83 | DNM1 (0.42) | DNM1CYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL15039491 | 0.72 | DNM1 (0.32) | DNM1CA12CA1CA2CA4 | |
| SCHEMBL15020203 | 0.72 | DNM1 (0.32) | DNM1CA12CA1CA2CA4 | |
| SCHEMBL15020202 | 0.72 | DNM1 (0.32) | DNM1CA12CA1CA2CA4 | |
| SCHEMBL11593134 | 0.72 | CYP3A4 (0.54) | CYP3A4TSHRALDH1A1MAPK1THRB | |
| SCHEMBL11785958 | 0.69 | RAPGEF4 (0.34) | CYP3A4TSHRALDH1A1MAPK1THRB | |
| SCHEMBL11388748 | 0.67 | DNM1 (0.47) | DNM1CYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL18334947 | 0.63 | CYP3A4 (0.49) | CYP3A4TSHRALDH1A1MAPK1THRB | |
| SCHEMBL11805905 | 0.62 | CYP3A4 (0.35) | CYP3A4TSHRALDH1A1MAPK1THRB | |
| SCHEMBL3786386 | 0.61 | TSHR (0.50) | CYP3A4TSHRALDH1A1MAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675130-A | HAIR DYES | L'OREAL (FR) | 1987-06-23 | — | — | US | disclosed |
| US-4246181-A | HAIR DYE | L'OREAL (FR) | 1981-01-20 | — | — | US | disclosed |