SCHEMBL10789403

SCHEMBL10789403

COc1c(C)ccc(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
PDE4A P27815 2/20 0.40
PDE4B Q07343 2/20 0.40
PDE4C Q08493 2/20 0.40
PDE4D Q08499 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
TRPA1 O75762 1/20 0.39
EPHX2 P34913 3/20 0.38
MAPT P10636 4/20 0.37
CYP3A4 P08684 2/20 0.37
ELANE P08246 1/20 0.37
KDM4E B2RXH2 2/20 0.36
MAPK1 P28482 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32612603 1.00 ALDH1A1 (0.43) ALDH1A1PDE4APDE4BPDE4CPDE4D
SCHEMBL11750586 0.85 MAOA (0.43) ALDH1A1PDE4APDE4BPDE4CPDE4D
SCHEMBL1053291 0.85 TP53 (0.43) ALDH1A1PDE4APDE4BPDE4CPDE4D
SCHEMBL7718393 0.83 MAPT (0.55) ALDH1A1TDP1EPHX2MAPTCYP3A4
SCHEMBL30364533 0.83 MAPT (0.46) ALDH1A1TDP1EPHX2MAPTCYP3A4
SCHEMBL12584714 0.83 MAPT (0.46) ALDH1A1TDP1EPHX2MAPTCYP3A4
SCHEMBL25276594 0.81 ALDH1A1 (0.42) ALDH1A1PDE4APDE4BPDE4CPDE4D
SCHEMBL25237707 0.81 MAPT (0.36) ALDH1A1PDE4APDE4BPDE4CPDE4D
SCHEMBL17368405 0.81 TUBB4A (0.39) ALDH1A1PDE4APDE4BPDE4CPDE4D
SCHEMBL30192941 0.80 ALDH1A1 (0.45) ALDH1A1TDP1MAPTCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109996776-A The method for preparing (more) alkylating phenol 帝斯曼知识产权资产管理有限公司 2019-07-09 CN disclosed
CN-108430962-A Intermolecular reaction of propargyl ether with dimethylfuran in the presence of gold (I) complex 帝斯曼知识产权资产管理有限公司 2018-08-21 CN disclosed
US-7157154-B2 Organoboron polymers; photoconductivity; inks; thin films; semiconductors; surface light sources; dot matrix displays SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-02 US disclosed
EP-0116442-B1 IMPROVED PROCESS FOR PREPARING POLYPHENYLENE ETHERS BORG-WARNER CHEMICALS INC. (US) 1987-07-22 EP disclosed
EP-0116442-A1 Improved process for preparing polyphenylene ethers BORG-WARNER CHEMICALS INC. (US) 1984-08-22 EP disclosed
US-4463164-A OXIDATIVELY COUPLING MONOHYDRIC PHENOLS IN LIQUID MIXTURE WHICH IS A SOLVENT FOR THE MONOMER BUT IN WHICH THE POLYMER PRECIPITATES BORG-WARNER CHEMICALS, INC. (US) 1984-07-31 US disclosed