Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32612603 | 0.85 | ALDH1A1 (0.43) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL10789403 | 0.85 | ALDH1A1 (0.43) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL29421886 | 0.83 | MAOA (0.44) | TP53CYP3A4MAPTTDP1MAOA | |
| SCHEMBL4294248 | 0.83 | MAOA (0.44) | TP53CYP3A4MAPTTDP1MAOA | |
| SCHEMBL11882012 | 0.82 | MAPT (0.48) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL23999210 | 0.81 | TRPA1 (0.41) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL11750586 | 0.81 | MAOA (0.43) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL768018 | 0.81 | SCN5A (0.52) | TP53CYP3A4TDP1TRPA1MAOA | |
| SCHEMBL30364533 | 0.79 | MAPT (0.46) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL12584714 | 0.79 | MAPT (0.46) | TP53KDM4EALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318477-B1 | ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES | FUJIFILM ELECTRONIC MAT USA INC (US) | 2019-06-05 | — | — | EP | disclosed |
| WO-2016155573-A1 | HETEROCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2016-10-06 | — | — | WO | disclosed |
| US-8252704-B2 | Additives to prevent degradation of cyclic alkene derivatives | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2012-08-28 | — | — | US | disclosed |
| US-20110259242-A1 | Additives to Prevent Degradation of Cyclic Alkene Derivatives | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-7985350-B2 | Additives to prevent degradation of cyclic alkene derivatives | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2011-07-26 | — | — | US | disclosed |
| EP-2318477-A1 | ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES | FujiFilm Electronic Materials USA, Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| US-20110091651-A1 | Additives to Prevent Degradation of Cyclic Alkene Derivatives | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-7871536-B2 | Additives to prevent degradation of cyclic alkene derivatives | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2011-01-18 | — | — | US | disclosed |
| WO-2010005937-A1 | ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20090291210-A1 | Additives to Prevent Degradation of Cyclic Alkene Derivatives | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2009-11-26 | — | — | US | disclosed |
| US-5019656-A | Hydroxymethylation of a Phenol, Basic Catalyst, Crown Compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0386639-A1 | Process for preparing para-hydroxybenzyl alcohol | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-3970640-A | Process for the production of polyphenylene ethers having a desired polymerization degree | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110259242-A1 | Additives to Prevent Degradation of Cyclic Alkene Derivatives | GPX4, GPX1, NFE2L2 | TP53 1201/4885KDM4E 2810/4885ALDH1A1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.