Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | FABP6 | P51161 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847296 | 0.94 | HRH3 (0.71) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| SCHEMBL24574127 | 0.94 | HRH3 (0.71) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| SCHEMBL10789534 | 0.94 | HRH3 (0.71) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| SCHEMBL294763 | 0.94 | HRH3 (0.71) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| Hydrochloric Acid SCHEMBL11781778 | 0.92 | HRH3 (0.69) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| Hydrochloric Acid SCHEMBL11782513 | 0.92 | HRH3 (0.69) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| SCHEMBL433970 | 0.92 | GRIN2B (0.69) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| Acetic Acid SCHEMBL8071956 | 0.91 | EPHX1 (0.60) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| Bromide SCHEMBL18131548 | 0.91 | HRH3 (0.67) | HRH3GRIN2BEPHX1HPGDTAAR1 | |
| Hydrochloric Acid SCHEMBL11785266 | 0.90 | GRIN2B (0.67) | HRH3GRIN2BEPHX1HPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210816-B1 | Translucent xerographic recording substrates | XEROX CORPORATION | 2001-04-03 | — | — | US | claimed |
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | disclosed |
| CN-108925135-A | Synthetic method for preparing (S) - (2R,3R,11bR) -3-isobutyl-9, 10-dimethoxy-2, 3,4,6,7,11 b-hexahydro-1H-pyrido [2,1-a ] isoquinolin-2-yl-2-amino-3-methylbutyrate bis (4-methylbenzenesulfonate) | 纽罗克里生物科学有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-104024241-B | Uracil derivatives and their use for medical purposes | DAINIPPON SUMITOMO PHARMA CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| US-9040516-B2 | Uracil derivative and use thereof for medical purposes | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| CN-104024241-A | Uracil derivatives and their use for medical purposes | DAINIPPON SUMITOMO PHARMA CO | 2014-09-03 | — | — | CN | disclosed |
| US-20140179670-A1 | URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| EP-2740728-A1 | URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2014-06-11 | — | — | EP | disclosed |
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| CN-101970572-B | Photocurable composition | SEKISUI CHEMICAL CO LTD | 2014-01-29 | — | — | CN | disclosed |
| EP-1911516-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-7199260-B2 | Process for reductive dehalogenation | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20060052626-A1 | Process for reductive dehaloganation | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |
| US-6825191-B2 | ANTICOAGULANT | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030186969-A1 | Benzodiazepine derivatives | AJINOMOTO CO. INC (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1329450-A1 | BENZODIAZEPINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2003-07-23 | — | — | EP | disclosed |
| CN-1358170-A | Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters | BIOCRYST PHARMACEUTICAL INC (US) | 2002-07-10 | — | — | CN | disclosed |
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6210816-B1 | Translucent xerographic recording substrates | XEROX CORPORATION | 2001-04-03 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186969-A1 | Benzodiazepine derivatives | GABRA1, F11, GABRA4 | HRH3 418/4885GRIN2B 221/4885EPHX1 1008/4885 |
| US-20060052626-A1 | Process for reductive dehaloganation | IDUA, CYP2F1, DEK | HRH3 1879/4885GRIN2B 3183/4885EPHX1 710/4885 |
| US-20140179670-A1 | URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | URB2, ELANE, NUDT1 | HRH3 51/4885GRIN2B 3111/4885EPHX1 1257/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | HRH3 4157/4885GRIN2B 4393/4885EPHX1 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.