Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | MTOR | P42345 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31392616 | 0.86 | ADRA2A (0.47) | ADRB2ADRB1ADRB3MAPTTSHR | |
| SCHEMBL31392618 | 0.77 | ADRA2A (0.46) | ADRB2ADRB1ADRB3MAPTTSHR | |
| SCHEMBL2987382 | 0.76 | ADRA2A (0.43) | MAPTTSHRTDP1HSD17B10ADRA1A | |
| Deterenol SCHEMBL31419987 | 0.74 | ADRB2 (0.67) | ADRB2ADRB1ADRB3MAPTTSHR | |
| Deterenol SCHEMBL828537 | 0.74 | ADRB2 (0.67) | ADRB2ADRB1ADRB3MAPTTSHR | |
| Isoproterenol SCHEMBL4165 | 0.74 | MAPT (1.00) | ADRB2ADRB1ADRB3MAPTTSHR | |
| Isoproterenol SCHEMBL29519146 | 0.74 | MAPT (1.00) | ADRB2ADRB1ADRB3MAPTTSHR | |
| Levisoprenaline SCHEMBL250806 | 0.74 | MAPT (1.00) | ADRB2ADRB1ADRB3MAPTTSHR | |
| Isoproterenol SCHEMBL3253794 | 0.74 | MAPT (1.00) | ADRB2ADRB1ADRB3MAPTTSHR | |
| Isoproterenol SCHEMBL4166 | 0.74 | MAPT (1.00) | ADRB2ADRB1ADRB3MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108145-B1 | DEVICE FOR DELIVERY OF A DRUG | Key Pharmaceuticals, Inc. (US) | 1987-08-19 | — | — | EP | claimed |
| US-4484577-A | Drug delivery method and inhalation device therefor | KEY PHARMACEUTICALS, INC. (US) | 1984-11-27 | — | — | US | claimed |
| EP-0108145-B1 | DEVICE FOR DELIVERY OF A DRUG | Key Pharmaceuticals, Inc. (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4484577-A | Drug delivery method and inhalation device therefor | KEY PHARMACEUTICALS, INC. (US) | 1984-11-27 | — | — | US | disclosed |
| EP-0108145-A4 | DEVICE FOR DELIVERY OF A DRUG. | KEY PHARMA (US) | 1984-09-28 | — | — | EP | disclosed |
| EP-0108145-A1 | DEVICE FOR DELIVERY OF A DRUG. | KEY PHARMA (US) | 1984-05-16 | — | — | EP | disclosed |
| WO-1983003976-A1 | DEVICE AND METHOD FOR DELIVERY OF A DRUG | KEY PHARMACEUTICALS, INC. (US) | 1983-11-24 | — | — | WO | disclosed |