Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868622 | 0.95 | THRA (0.56) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL23069656 | 0.94 | THRA (0.58) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL27509209 | 0.94 | THRA (0.58) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL10359207 | 0.92 | THRA (0.57) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL31493123 | 0.92 | THRA (0.57) | THRATHRBPPARAPPARGPTGS2 | |
| Ethylene Glycol SCHEMBL11870625 | 0.87 | THRA (0.55) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL4275189 | 0.87 | MTNR1A (0.42) | THRATHRBPPARAPPARGMTNR1A | |
| SCHEMBL15648198 | 0.85 | THRA (0.49) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL8619436 | 0.84 | L3MBTL1 (0.46) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL1788428 | 0.83 | PPARG (0.62) | THRATHRBPPARAPPARGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639499-A | UNSATURATED DIOL, CAPROLACTONE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |