Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL2230974 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL15641846 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL15641844 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1151273 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL4274563 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1072 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735413-A1 | CRYSTALLIZATION METHOD FOR PURIFIED TEREPHTHALIC ACID | DePoly SA (CH) | 2026-05-06 | — | — | EP | claimed |
| CN-119873968-A | Embedded-based materials and processes for softening water | 罗伯特·博世有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119751238-A | Preparation method of p-tert-butylbenzoic acid and p-tert-butylbenzoic acid | 江西永通科技股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2025007381-A1 | HIGH-TEMPERATURE THERMAL INITIATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 湖北及安盾消防科技有限公司 | 2025-01-09 | — | — | WO | claimed |
| WO-2025000111-A1 | CRYSTALLIZATION METHOD FOR PURIFIED TEREPHTHALIC ACID | DEPOLY SA (CH) | 2025-01-02 | — | — | WO | claimed |
| WO-2025000625-A1 | CHEMICAL COOLANT AND USE THEREOF IN AEROSOL-BASED FIRE EXTINGUISHING | 湖北及安盾消防科技有限公司 | 2025-01-02 | — | — | WO | claimed |
| WO-2024192847-A1 | ENVIRONMENT-FRIENDLY MULTI-CORE MOISTURE-PROOF THERMOSENSITIVE WIRE AND MANUFACTURING METHOD THEREFOR | 湖北及安盾消防科技有限公司 | 2024-09-26 | — | — | WO | claimed |
| CN-118108554-A | Reducing agent for preparing firework propellant | 万载县建坤化工有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-116393145-B | Ga doped In2S3Preparation method and application of catalyst | 广东石油化工学院 | 2024-04-26 | — | — | CN | claimed |
| CN-117362919-A | PEEK/UiO-66 composite material and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2024-01-09 | — | — | CN | claimed |
| CN-101705070-A | Method for preparing quickly-crystallized polyester hot melt adhesive | UNIV EAST CHINA SCIENCE & TECH | 2010-05-12 | — | — | CN | claimed |
| CN-101407510-A | Preparation of duloxetine hydrochloride intermediate | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2009-04-15 | — | — | CN | claimed |
| US-20080260948-A1 | INK AND INK JET RECORDING METHOD | CANON KABUSHIKI KAISHA (JP) | 2008-10-23 | — | — | US | claimed |
| US-5175354-A | Reacting the potassium salt with benzenecarboxylic acid | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1992-12-29 | — | — | US | claimed |
| US-4737540-A | MOLDINGS HAVING MINIMIZED SINK MARKS | MITSUBISHI RAYON CO., LTD. (JP) | 1988-04-12 | — | — | US | claimed |
| US-4625056-A | Process for producing benzene carboxylic acids from aromatic material utilizing an aliphatic organic acid agent | OCCIDENTAL RESEARCH CORPORATION (US) | 1986-11-25 | — | — | US | claimed |
| US-4368283-A | HEAT RESISTANT MOLDING MATERIALS | MITSUBISHI RAYON CO., LTD. (JP) | 1983-01-11 | — | — | US | claimed |
| US-4345098-A | HYDROLYSIS, OXIDATION, ISOMERIZATION | OCCIDENTAL RESEARCH CORPORATION (US) | 1982-08-17 | — | — | US | claimed |
| US-4200586-A | Inhibiting the carbon-carbon double bond isomerization of substituted or unsubstituted hydrocarbon compounds | PHILLIPS PETROLEUM COMPANY (US) | 1980-04-29 | — | — | US | claimed |
| US-3952052-A | Process for producing alkali metal salts of aromatic polycarboxylic acids | PHILLIPS PETROLEUM COMPANY (US) | 1976-04-20 | — | — | US | claimed |