Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892214 | 0.90 | ALPL (0.55) | ALPLKMT2ASMN1; SMN2MAPTMCL1 | |
| SCHEMBL15212571 | 0.85 | ALPL (0.50) | ALPLKMT2ASMN1; SMN2MAPTMCL1 | |
| SCHEMBL10792479 | 0.80 | KDM4E (0.46) | ALPLKMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL10879548 | 0.78 | KMT2A (0.58) | KMT2ASMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL8533619 | 0.78 | KMT2A (0.60) | KMT2ASMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL16326383 | 0.77 | RAB9A (0.54) | KMT2ASMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL12892192 | 0.77 | KDM4E (0.46) | ALPLKMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL12892208 | 0.77 | ALOX5 (0.51) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10788839 | 0.76 | CYP2C9 (0.46) | KMT2ASMN1; SMN2HTTMEN1ALDH1A1 | |
| SCHEMBL10647360 | 0.74 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2HTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135032-B1 | CARBAMATES AND OXALYL AMIDES OF AMINO-N-(1H-TETRAZOL-5-YL) BENZAMIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4526979-A | Carbamates and oxalamides of amino-N-(1H-tetrazol-5-yl)benzamides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0135032-A1 | Carbamates and oxalyl amides of amino-N-(1H-tetrazol-5-yl) benzamides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-03-27 | — | — | EP | disclosed |