Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795503 | 0.82 | TAAR1 (0.46) | POLBTAAR1ARACP1GPR84 | |
| SCHEMBL10792280 | 0.81 | SMN1; SMN2 (0.49) | LMNATAAR1SMN1; SMN2ARKMT2A | |
| SCHEMBL16016408 | 0.80 | MPO (0.42) | LMNASMN1; SMN2GPR84 | |
| SCHEMBL6247431 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL10885165 | 0.76 | FABP4 (0.37) | PARP1 | |
| SCHEMBL3840210 | 0.74 | HSP90AB1 (0.45) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL82538 | 0.73 | TAAR1 (0.43) | POLBTAAR1SMN1; SMN2MEN1KMT2A | |
| Water SCHEMBL10981448 | 0.71 | TAAR1 (0.42) | POLBTAAR1SMN1; SMN2 | |
| SCHEMBL10791891 | 0.71 | DAO (0.42) | TAAR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10792269 | 0.71 | GPR84 (0.38) | TAAR1SMN1; SMN2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |