SCHEMBL1079150

SCHEMBL1079150

NCCCCCN[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 8/20 0.47
CPB1 P15086 1/20 0.46
ITGB3 P05106 10/20 0.36
ITGA2B P08514 10/20 0.36
SLC15A2 Q16348 1/20 0.35
TLR2 O60603 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776305 0.95 CPB2 (0.49) CPB2CPB1ITGB3ITGA2BSLC15A2
SCHEMBL3839540 0.89 CPB2 (0.55) CPB2CPB1SLC15A2
SCHEMBL3845157 0.89 CPB2 (0.55) CPB2CPB1SLC15A2
SCHEMBL30978072 0.87 CPB2 (0.51) CPB2CPB1ITGB3ITGA2BTLR2
SCHEMBL19138220 0.87 CPB2 (0.51) CPB2CPB1ITGB3ITGA2BTLR2
SCHEMBL38650912 0.87 CPB2 (0.51) CPB2CPB1ITGB3ITGA2BTLR2
SCHEMBL29503862 0.87 CPB2 (0.51) CPB2CPB1ITGB3ITGA2BTLR2
SCHEMBL19138219 0.87 CPB2 (0.51) CPB2CPB1ITGB3ITGA2BTLR2
SCHEMBL1667027 0.87 CPB2 (0.51) CPB2CPB1ITGB3ITGA2BTLR2
SCHEMBL11499161 0.87 CPB2 (0.40) CPB2CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140086855-A1 COMBINED USE OF A CARNOSINASE INHIBITOR WITH L-CARNOSINE OR ITS RELATED SUBSTANCE AND A COMPOSITION CONTAINING THE SAME INNOVATIVE VISION PRODUCTS, INC. (US) 2014-03-27 US claimed
US-20220395489-A1 THERAPEUTIC APPROACH FOR TREATING INFLAMMATORY BOWEL DISEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-12-15 US disclosed
US-20140086855-A1 COMBINED USE OF A CARNOSINASE INHIBITOR WITH L-CARNOSINE OR ITS RELATED SUBSTANCE AND A COMPOSITION CONTAINING THE SAME INNOVATIVE VISION PRODUCTS, INC. (US) 2014-03-27 US disclosed
US-20110151053-A1 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE NORTH CAROLINA STATE UNIVERSITY (US) 2011-06-23 US disclosed
US-7897367-B2 Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore NORTH CAROLINA STATE UNIVERSITY (US) 2011-03-01 US disclosed
US-20110020900-A1 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE NORTH CAROLINA STATE UNIVERSITY (US) 2011-01-27 US disclosed
EP-1122307-B1 Human carnosinase 2 SANOFI AVENTIS (FR) 2009-04-22 EP disclosed
US-7455992-B2 Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore NORTH CAROLINA STATE UNIVERSITY (US) 2008-11-25 US disclosed
EP-1871868-A2 METHODS AND COMPOSITIONS TO MODULATE ADHESION AND STRESS TOLERANCE IN BACTERIA North Carolina State University (US) 2008-01-02 EP disclosed
US-7186816-B2 Photolyase nucleic acids THE GENERAL HOSPITAL CORPORATION (US) 2007-03-06 US disclosed
US-20070003667-A1 Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore NORTH CAROLINA STATE UNIVERSITY 2007-01-04 US disclosed
WO-2006113475-A2 METHODS AND COMPOSITIONS TO MODULATE ADHESION AND STRESS TOLERANCE IN BACTERIA NORTH CAROLINA STATE UNIVERSITY (US) 2006-10-26 WO disclosed
US-20060116328-A1 Combined use of carnosinase inhibitor with l-carnosines and composition INNOVATIVE VISION PRODUCTS, INC. 2006-06-01 US disclosed
EP-1586332-A1 COMBINED USE OF CARNOSINASE INHIBITOR WITH L-CARNOSINES AND COMPOSITION Innovative Vision Products, Inc. (US) 2005-10-19 EP disclosed
WO-2005081959-A2 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFOR NORTH CAROLINA STATE UNIVERSITY (US) 2005-09-09 WO disclosed
US-20040214208-A1 Enterococcal virulence factors GENERAL HOSPITAL CORPORATION, THE 2004-10-28 US disclosed
US-6632636-B1 Use of vectors, host cells and methods for producing Moraxella catarrhalis proteins, or portions thereof, for identification of diagnostic and therapeutic compositions ELITRA PHARMACEUTICALS INC. 2003-10-14 US disclosed
WO-2003056295-A2 ENTEROCOCCAL VIRULENCE FACTORS THE GENERAL HOSPITAL CORPORATION (US) 2003-07-10 WO disclosed
EP-1122307-A1 Human carnosinase 2 SANOFI-SYNTHELABO (FR) 2001-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060116328-A1 Combined use of carnosinase inhibitor with l-carnosines and composition LCT, ADH1C, PON1 CPB2 550/4885CPB1 223/4885ITGB3 4835/4885
US-20140086855-A1 COMBINED USE OF A CARNOSINASE INHIBITOR WITH L-CARNOSINE OR ITS RELATED SUBSTANCE AND A COMPOSITION CONTAINING THE SAME LCT, CPA1, ADH1C CPB2 379/4885CPB1 146/4885ITGB3 4842/4885
US-20220395489-A1 THERAPEUTIC APPROACH FOR TREATING INFLAMMATORY BOWEL DISEASE FABP2, SI, VIP CPB2 90/4885CPB1 130/4885ITGB3 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.