Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049916 | 0.89 | HPGDS (0.43) | CYP11B1CYP11B2KDM5BSMN1; SMN2KMT2A | |
| SCHEMBL10792247 | 0.84 | CYP11B1 (0.39) | CYP11B1CYP11B2KDM5BSMN1; SMN2KMT2A | |
| SCHEMBL10792085 | 0.82 | CYP11B1 (0.47) | CYP11B1CYP11B2KDM5BSMN1; SMN2PTGS1 | |
| SCHEMBL6965586 | 0.80 | THRB (0.39) | CYP11B1CYP11B2SMN1; SMN2LMNAHTT | |
| SCHEMBL10630490 | 0.80 | CYP2C9 (0.44) | CYP11B1CYP11B2KDM5BSMN1; SMN2PTGS1 | |
| SCHEMBL24844768 | 0.79 | CYP11B1 (0.53) | CYP11B1CYP11B2KDM5BSMN1; SMN2PTGS1 | |
| SCHEMBL24845635 | 0.79 | CYP11B1 (0.53) | CYP11B1CYP11B2KDM5BSMN1; SMN2PTGS1 | |
| SCHEMBL10791602 | 0.79 | PHF8 (0.44) | CYP11B1CYP11B2KDM5BSMN1; SMN2KMT2A | |
| SCHEMBL10795248 | 0.77 | PHF8 (0.50) | KDM5BSMN1; SMN2KMT2ARAB9ALMNA | |
| SCHEMBL10792191 | 0.76 | CYP11B1 (0.39) | CYP11B1CYP11B2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |