Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958763 | 0.85 | PHF8 (0.34) | KDM4EPHF8CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL6972372 | 0.85 | ALDH1A1 (0.42) | KDM4ETP53HTTLTA4H | |
| SCHEMBL6955809 | 0.85 | HPGDS (0.39) | PHF8CYP11B1CYP11B2CYP2A6CYP19A1 | |
| SCHEMBL11049916 | 0.85 | HPGDS (0.43) | LMNAPHF8CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL6968287 | 0.83 | NR1H2 (0.38) | KDM4EPHF8LTA4H | |
| SCHEMBL10791998 | 0.80 | CYP11B1 (0.51) | KDM4ELMNACYP11B1CYP11B2HTT | |
| SCHEMBL6968013 | 0.77 | KDM4C (0.40) | PHF8CYP11B1CYP11B2 | |
| SCHEMBL6952807 | 0.76 | SIGMAR1 (0.45) | PHF8CYP11B1CYP11B2CYP2A6CYP19A1 | |
| SCHEMBL10792191 | 0.75 | CYP11B1 (0.39) | KDM4ELMNACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6972346 | 0.74 | PHF8 (0.38) | LMNAPHF8CYP2A6CYP19A1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |