Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694861 | 0.93 | PTGS2 (0.37) | PTGESPTGS2MRGPRX1MAOB | |
| SCHEMBL3697908 | 0.91 | PTGES (0.36) | PTGESPTGS2MRGPRX1 | |
| SCHEMBL3704804 | 0.91 | PTGES (0.36) | PTGESPTGS2MRGPRX1MAOB | |
| SCHEMBL3694433 | 0.90 | PTGS2 (0.36) | PTGESPTGS2MRGPRX1 | |
| SCHEMBL1081379 | 0.88 | PTGES (0.51) | PTGESPTGS2 | |
| SCHEMBL1079353 | 0.86 | PTGES (0.43) | PTGESPTGS2 | |
| SCHEMBL1081836 | 0.86 | PTGES (0.45) | PTGESPTGS2MRGPRX1MAOB | |
| SCHEMBL1080114 | 0.85 | SMN1; SMN2 (0.37) | PTGES | |
| SCHEMBL1177252 | 0.85 | PTGS2 (0.50) | PTGESPTGS2 | |
| SCHEMBL3700948 | 0.83 | MAOB (0.34) | PTGESMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |
| EP-2268625-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009127338-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |