Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694861 | 0.93 | PTGS2 (0.37) | PTGESPTGS2MRGPRX1PPARGPPARA | |
| SCHEMBL1079351 | 0.91 | PTGES (0.38) | PTGESPTGS2MRGPRX1 | |
| SCHEMBL3704804 | 0.90 | PTGES (0.36) | PTGESPTGS2MRGPRX1 | |
| SCHEMBL3694433 | 0.89 | PTGS2 (0.36) | PTGESPTGS2MRGPRX1 | |
| SCHEMBL1078521 | 0.88 | PTGES (0.49) | PTGESPTGS2 | |
| SCHEMBL1178914 | 0.87 | PTGES (0.41) | PTGESPTGS2 | |
| SCHEMBL1177252 | 0.84 | PTGS2 (0.50) | PTGESPTGS2 | |
| SCHEMBL1081836 | 0.84 | PTGES (0.45) | PTGESPTGS2MRGPRX1PPARG | |
| SCHEMBL3700948 | 0.83 | MAOB (0.34) | PTGES | |
| SCHEMBL1069734 | 0.81 | PTGS2 (0.33) | PTGESPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |