Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799308 | 0.82 | MAPT (0.39) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL10794161 | 0.76 | KCNN4 (0.36) | MAPTGAALMNAMEN1KMT2A | |
| SCHEMBL12368472 | 0.72 | RAPGEF4 (0.56) | RAPGEF4MAPTGAAKDM4ELMNA | |
| SCHEMBL13909756 | 0.69 | RAPGEF4 (0.58) | RAPGEF4MAPTGAALMNAPOLB | |
| SCHEMBL10799298 | 0.68 | HPGD (0.45) | MAPTGAALMNAMEN1KMT2A | |
| SCHEMBL6821181 | 0.68 | GAA (0.59) | RAPGEF4MAPTGAAKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL403976 | 0.66 | GAA (0.58) | RAPGEF4MAPTGAAKDM4ELMNA | |
| SCHEMBL28589516 | 0.66 | MAPT (0.45) | RAPGEF4MAPTGAAKDM4ELMNA | |
| SCHEMBL9232234 | 0.66 | RAPGEF4 (0.57) | RAPGEF4MAPTGAAKDM4ELMNA | |
| SCHEMBL27924446 | 0.66 | RAPGEF4 (0.57) | RAPGEF4MAPTGAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088667-B1 | HALOGENATED AROMATIC DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-04-08 | — | — | EP | claimed |