Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799308 | 0.86 | MAPT (0.39) | KCNN4MEN1KMT2ATSHRGAA | |
| SCHEMBL10794154 | 0.76 | RAPGEF4 (0.45) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL10799298 | 0.69 | HPGD (0.45) | KCNN4PTGS2MEN1KMT2ATSHR | |
| SCHEMBL4037942 | 0.69 | CD44 (0.39) | CLCN2CD44GAALMNAMAPT | |
| SCHEMBL22946826 | 0.67 | ALDH1A1 (0.38) | MAPK1CD44TSHRMAPTHTT | |
| SCHEMBL10798800 | 0.66 | CLCN2 (0.35) | PTGS2TTRMEN1AKR1B10ABCB11 | |
| SCHEMBL23113993 | 0.65 | KEAP1 (0.39) | PTGS2TTRMEN1AKR1B10ABCB11 | |
| SCHEMBL11411291 | 0.65 | CLCN2 (0.39) | PTGS2TTRMEN1AKR1B10ABCB11 | |
| SCHEMBL20688029 | 0.65 | ALDH1A1 (0.38) | PTGS2TTRMEN1AKR1B10ABCB11 | |
| SCHEMBL21938340 | 0.65 | MAPT (0.37) | PTGS2TTRMEN1AKR1B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088667-B1 | HALOGENATED AROMATIC DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-04-08 | — | — | EP | claimed |