Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12974365 | 0.75 | HPGD (0.50) | HPGDHTTKIF11MAPTNPC1 | |
| SCHEMBL10799308 | 0.74 | MAPT (0.39) | HPGDHTTMAPTGAATDP1 | |
| SCHEMBL14917528 | 0.72 | HPGD (0.47) | HPGDHTTKIF11MAPTGAA | |
| SCHEMBL11087192 | 0.71 | KIF11 (0.53) | HPGDKIF11TDP1TSHRKCNN4 | |
| P-Xylene SCHEMBL29242628 | 0.71 | TSHR (0.74) | HPGDKIF11TDP1TSHRKCNN4 | |
| SCHEMBL10794161 | 0.69 | KCNN4 (0.36) | HTTMAPTGAATSHRKCNN4 | |
| SCHEMBL7644095 | 0.69 | TSHR (0.48) | HPGDHTTKIF11TDP1SMN1; SMN2 | |
| SCHEMBL17336268 | 0.69 | KCNN4 (0.70) | HPGDKIF11TDP1TSHRKCNN4 | |
| SCHEMBL2484318 | 0.69 | TSHR (0.48) | HPGDHTTKIF11TDP1SMN1; SMN2 | |
| SCHEMBL118809 | 0.69 | TSHR (0.48) | HPGDHTTKIF11TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088667-B1 | HALOGENATED AROMATIC DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-04-08 | — | — | EP | claimed |