Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998948 | 0.83 | MME (0.54) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL999188 | 0.73 | CTSK (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5934705 | 0.72 | CTSK (0.58) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL27494131 | 0.70 | CTSK (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL31512922 | 0.70 | CTSK (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7345223 | 0.69 | CTSK (0.45) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL31512926 | 0.68 | CTSK (0.52) | CTSKCTSSCTSLCTSB | |
| SCHEMBL31512929 | 0.68 | CTSK (0.52) | CTSKCTSSCTSLCTSB | |
| SCHEMBL31512935 | 0.68 | CTSK (0.58) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL18174177 | 0.68 | ALDH1A1 (0.47) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467144-A1 | COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS | ViroLogik GmbH (DE) | 2012-06-27 | — | — | EP | claimed |
| WO-2011009961-A1 | COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS | VIROLOGIK GMBH (DE) | 2011-01-27 | — | — | WO | claimed |
| EP-1326632-B1 | PROTEASOME INHIBITORS FOR THE TREATMENT OF HEPATITIS VIRUS INFECTIONS | VIROMICS GMBH (DE) | 2006-09-06 | — | — | EP | claimed |
| WO-2011089167-A1 | KOMBINATION OF PROTEASOME INHIBITORS AND ANTI -HEPATITIS MEDICATION FOR TREATING RETROVIRAL DISEASES | VIROLOGIK GMBH (DE) | 2011-07-28 | — | — | WO | disclosed |