Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 4/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999188 | 0.85 | CTSK (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL31512922 | 0.83 | CTSK (0.56) | MMECTSKCTSSCTSLCTSB | |
| SCHEMBL1079423 | 0.83 | CTSK (0.44) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5193478 | 0.82 | CTSK (0.49) | MMECTSKECE1CTSSCTSL | |
| SCHEMBL1524821 | 0.81 | CTSK (0.52) | MMECTSKECE1CTSSCTSL | |
| SCHEMBL5934705 | 0.81 | CTSK (0.58) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL29861104 | 0.81 | MME (0.52) | MMECTSKECE1CAPN1 | |
| SCHEMBL8764285 | 0.80 | MMP1 (0.53) | MMECAPN1 | |
| SCHEMBL25406813 | 0.80 | CTSK (0.77) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL8823918 | 0.80 | CTSK (0.77) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467144-A1 | COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS | ViroLogik GmbH (DE) | 2012-06-27 | — | — | EP | claimed |
| WO-2011009961-A1 | COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS | VIROLOGIK GMBH (DE) | 2011-01-27 | — | — | WO | claimed |