Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174177 | 0.93 | ALDH1A1 (0.47) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL19586697 | 0.91 | TPSAB1 (0.46) | CTSKCTSBCTSSCTSLALDH1A1 | |
| Water SCHEMBL1238348 | 0.90 | TPSAB1 (0.45) | CTSKCTSBCTSSCTSL | |
| SCHEMBL10537523 | 0.90 | CTSK (0.44) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL7000046 | 0.87 | CTSK (0.57) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL2300007 | 0.87 | CTSK (0.57) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL2497060 | 0.87 | CTSK (0.57) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL11433447 | 0.86 | SLC1A1 (0.41) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL10443784 | 0.86 | SLC15A1 (0.46) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL31520502 | 0.86 | CTSK (0.41) | CTSKCTSBCTSSCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467144-A1 | COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS | ViroLogik GmbH (DE) | 2012-06-27 | — | — | EP | disclosed |
| WO-2011009961-A1 | COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS | VIROLOGIK GMBH (DE) | 2011-01-27 | — | — | WO | disclosed |
| EP-0181071-A2 | Amino acid ester and amide renin inhibitors | E.R. Squibb & Sons, Inc. (US) | 1986-05-14 | — | — | EP | disclosed |