Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515423 | 1.00 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1692431 | 1.00 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine SCHEMBL11133474 | 0.95 | SLC7A5 (0.65) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Pyrrole SCHEMBL28176452 | 0.93 | ALPI (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL10458393 | 0.93 | ALPI (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Tyrosine SCHEMBL28813646 | 0.89 | SLC7A5 (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL4268012 | 0.86 | ALDH1A1 (0.42) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL607242 | 0.86 | SLC7A5 (0.56) | SLC7A5CYP3A4ALDH1A1HSD17B10HDAC8 | |
| SCHEMBL598432 | 0.86 | SLC7A5 (0.56) | SLC7A5CYP3A4ALDH1A1HSD17B10HDAC8 | |
| SCHEMBL19472012 | 0.85 | SLC7A5 (0.51) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585142-B | Novel antimalarial compounds, method for the production thereof and use thereof for the resistance of malaria | 科学与工业研究会 | 2024-01-19 | — | — | CN | claimed |
| CN-112585142-A | Novel antimalarial compounds, preparation method and use thereof for drug-resistant malaria | 科学与工业研究会 | 2021-03-30 | — | — | CN | claimed |
| WO-2008096373-A2 | PROCESS FOR SYNTHESIZING HIGHLY PURE NATEGLINIDE POLYMORPHS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-08-14 | — | — | WO | claimed |
| CN-1849298-A | Production of N-acyl compounds | SOLVAY FLUOR GMBH (DE) | 2006-10-18 | — | — | CN | claimed |
| US-20060217533-A1 | Production of N-acyl compounds | SOLVAY FLUOR GMBH (DE) | 2006-09-28 | — | — | US | claimed |
| EP-0220923-B1 | Dipeptides and process | GRACE W R & CO (US) | 1994-04-27 | — | — | EP | claimed |
| EP-0269390-B1 | ENZYMATIC L-ASPARTYL-L-PHENYLALANINE ALKYL ESTER PRODUCTION | GENENCOR INTERNATIONAL, INC. (US) | 1993-08-25 | — | — | EP | claimed |
| EP-0269390-A2 | Enzymatic L-aspartyl-L-phenylalanine alkyl ester production | GENENCOR INTERNATIONAL, INC. (US) | 1988-06-01 | — | — | EP | claimed |
| US-4709075-A | REACTING ALKYL L-PHENYLALANATE AND MALEIC ANHYDRIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | claimed |
| EP-0074095-B1 | PROCESS FOR PREPARATION OF ASPARTYLPHENYLALANINE ALKYL ESTERS | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1986-04-30 | — | — | EP | claimed |
| EP-0169937-A2 | Process for the preparation of alpha-L-aspartyl-L-phenylalanine alkyl esters | FARCHEMIA S.p.A. (IT) | 1986-02-05 | — | — | EP | claimed |
| US-4539147-A | 3,5-DIMETHOXY-2,2-DIMETHYLBENZYLOXYCARBONYL GROUP TO PROTECT AMINE OF ASPARTIC ACID | SIRAC SPA (IT) | 1985-09-03 | — | — | US | claimed |
| EP-0149594-A2 | Enzymatic coupling of n-formyl amino acids and/or peptide residues | Monsanto Company (US) | 1985-07-24 | — | — | EP | claimed |
| EP-0102483-A1 | Process for preparing alpha-l-aspartyl-l-phenylalanine alkyl esters | SIRAC SRL (IT) | 1984-03-14 | — | — | EP | claimed |
| EP-0030076-B1 | PURIFICATION OF L-ASPARTYL-L-PHENYLALANINE ALKYL ESTERS | PFIZER INC. (US) | 1983-10-19 | — | — | EP | claimed |
| EP-0030076-A1 | Purification of L-aspartyl-L-phenylalanine alkyl esters | PFIZER INC. (US) | 1981-06-10 | — | — | EP | claimed |
| US-4238392-A | Purification of L-aspartyl-L-phenylalanine alkyl esters | PFIZER INC. (US) | 1980-12-09 | — | — | US | claimed |
| US-3983162-A | Optical resolution of alkyl esters of DL-phenylalanine | G. D. SEARLE & CO. (US) | 1976-09-28 | — | — | US | claimed |
| JP-1160495-A | — | — | None | — | — | JP | disclosed |
| US-3933781-A | Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters | MONSANTO COMPANY (US) | 1976-01-20 | — | — | US | disclosed |